epigenetics

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Are you, or someone you know, thinking about starting a family now or in the near future? Typically, the focus on reproductive health falls on the woman, and it begins after conception has already occurred, with minimal emphasis on diet and nutrition beyond prenatal vitamins. 

However, the pre-conception window is a foundational time for both partners to take charge of their hormonal, metabolic, and overall health to ensure the healthiest sperm and egg possible for a healthy pregnancy and, most importantly, a healthy baby. 

In today's episode, we're discussing the essential steps both men and women can take to foster a nurturing environment for conception. We'll delve into lab tests and tools to support hormone and reproductive wellness, the challenges and insults of our modern-day lifestyles, and how we can use Functional Medicine to take a proactive approach by embracing diet, supplements, and exercise to prime couples for a successful pregnancy while safeguarding against developmental conditions like autism and ADHD that are doubling, or even tripling from one generation to the next. 

Whether you're just starting to think about having kids or already on your pregnancy path, this conversation is for you. 

In this episode I discuss: 

• The importance of the preconception window (3:15)(5:05)
• How epigenetics impact the preconception window (3:58)(6:01)
• How parent’s diet and lifestyle imprint their children’s epigenome (5:03)(6:59)
• Limitations of Conventional Medicine during the preconception window (9:30)(11:26)
• The Functional Medicine approach to preparing to conceive (12:12)
• Breakdown of essential nutrients and biomarkers to ensure a healthy pregnancy (15:27)
• Sex hormone and bonus lab tests (21:00)
• Optimizing blood sugar and cardiometabolic health before and during pregnancy (22:40)
• Foods to eat and foods to avoid while gearing up for pregnancy (23:44)
• Eat your foods in the correct order (protein and fat first, then carbs (36:28)
• Tips for reducing exposure to endocrine-disrupting chemicals (38:14)
• The power of exercise, stress, and sleep for a healthy pregnancy (47:24)
• Supplement recommendations for men and women for the preconception window (51:35)

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Here on the ADHD Women's Wellbeing Podcast, I'm passionate about bringing you the conversations that improve well-being and quality of life after a late-in-life ADHD diagnosis.

Today, we have another show-stopper of an episode! In today's discussion, we discuss the latest findings in epigenetics, neuroscience and nutrition with Dr Rachel V. Gow, PhD, nutritional Neuroscientist, Neuropsychologist and Neurodevelopmental specialist with expertise in various mental health conditions and associative learning and behaviour differences. In addition, Dr. Gow is

Dr Gow, also a registered nutritionist, has published 22 peer-reviewed book chapters and scientific papers. She has extensive knowledge of neurodiverse learning and behavioural differences and the effects of dopamine-enhancing brain‐selective nutrients. Her book - “Smart Foods for ADHD and Brain Health” - is available on Amazon.

In this episode of the ADHD Women's Wellbeing Podcast, Kate and Rachel spoke about:

• Rachael's upbringing and how she became a young mum
• Being an ambitious, single parent
• Battling the stigma of ADHD in the school system 20+ years ago
• Raising a neurodivergent child as a young mother in the 90s
• What Rachael learnt about food and the link to her son's behaviour
• Why Dr Gow wanted to study nutrition and neuroscience
• The connection between diet and ADHD symptoms and behaviour
• The impacts of ultra-processed food on the ADHD brain and gut
• The effects of dietary sugar on the brain
• Addiction, dopamine and the ADHD brain
• Cooking whole foods and involving your children
• New findings that suggest Epigenetics play a role in ADHD
• Using lifestyle to support our epigenetics
• Implementing nutritional changes for an ADHD family
• Making changes in our lifestyle and nutrition to celebrate

Kate's new four-part workshop series, Regulating Your ADHD Nervous System, is available here.

Kate Moryoussef is a women’s ADHD Lifestyle & Wellbeing coach and EFT practitioner helping overwhelmed and unfulfilled newly-diagnosed ADHD women find more calm, balance, hope, health, compassion, creativity and clarity. 

Have a look at some of Kate's workshops and free resources here.

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Find Kate's resources on ADDitude magazine here

Mentioned in this episode:

Regulating Your ADHD Nervous System Workshop

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Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this episode, Alex delves into two interconnected topics: liquid biopsies and epigenetics. He begins by tracing the trajectory of genome sequencing and tumor sequencing, setting the stage for a detailed exploration of liquid biopsies as an early cancer detection method. The discussion encompasses key concepts such as cell-free DNA, DNA methylation, sensitivity, specificity, and the predictive values associated with liquid biopsies. Transitioning to epigenetics, Alex examines the intricate interplay of DNA methylation and aging biology and explores the possibility of using cellular reprogramming to reverse epigenetic changes that occur with aging.

We discuss:

• Alex’s background in applying engineering to problems in medicine [3:15];
• A primer on human genetics, and the history and current landscape of DNA sequencing [11:00];
• The advent and evolution of liquid biopsies for early detection of cancer [23:15];
• The role of cell-free DNA in cancer detection: how incidental findings in non-invasive prenatal testing led to the development of liquid biopsies [40:15];
• The development of a universal blood test for cancer detection and a discussion of specificity of tests [46:00];
• Advancements in cell-free DNA analysis and development of a multi-cancer screening test at GRAIL [51:00];
• DNA methylation explained [58:15];
• Optimizing cancer detection with methylation analysis of cfDNA in small blood samples [1:02:45];
• The importance of understanding sensitivity, specificity, positive predictive value, and negative predictive value in cancer screening [1:08:00];
• The performance of the GRAIL Galleri test and its ability to detect various types and stages of cancer [1:21:00];
• Do early cancer detection methods, like liquid biopsies, translate to improvement in overall survival? [1:27:45];
• The role of epigenetics in aging [1:39:30];
• How cell-free DNA methylation patterns can help identify a cancer’s tissue of origin [1:45:30];
• Cellular and epigenetic reprogramming and other exciting work in the field of aging [1:52:30]; and
• More.

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This one’s got it all: teeny tiny cellular factories, mitochondrial relevancy, what big smelly vats of poop have to do with curing cancer, how many trips to the sun your unravelled DNA could make, and mysteries of the brain. Dr. Raven The Science Maven has a background in molecular biology and a Ph.D in Science Communication, which she puts to work while Alie generally does her best to suppress high pitched noises of excitement. Learn to appreciate your proteins and pick up some noodle analogies while you’re here. That’s so Maven!

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Full-length (*not* G-rated) Molecular Biology episode + tons of science links

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Deepak Chopra is a world-renowned pioneer in integrative medicine and personal transformation and the founder of the Chopra Foundation and Chopra Global. Deepak is a clinical professor of family medicine and public health at the University of California, San Diego, and serves as a senior scientist with the Gallup Organization. He is the author of more than ninety books translated into forty-three languages, including numerous New York Times bestsellers. 

This episode is brought to you by Rupa Health, BiOptimizers, Levels, and Armra.

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In this episode, we discuss (audio version / Apple Subscriber version):

• The quantum field (6:13 / 4:30)
• What is the quantum body and how is it different from your physical body? (13:06 / 11:23)
• How our perception of time affects health and aging (15:52 / 14:09)
• The qualia field and where our experiences come from (20:17 / 18:34)
• The parasympathetic nervous system and the healing response activated by stimulating the vagus nerve (26:25 / 24:42)
• Why disease can become optional (33:08 / 31:25)
• Quantum metabolism and how information changes your metabolism (40:21 / 36:15)
• How to shift the aging process (46:04 / 43:58)
• How Deepak has overcome the fear of death (50:20 / 46:14)
• The four intentions Deepak starts his day with (54:53 / 50:48)

Get a copy of Quantum Body: The New Science of Living a Longer, Healthier, More Vital Life.

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This episode is brought to you by Rupa Health, Sensate, and Super Simple Protein. 

Epigenetics is the study of how our environment and behavior can influence which of our genes are turned on or off. That’s right—we’re born with many different genes, but that does not mean they are all active. Genes can be activated or silenced from so many different things, like what you eat, how you move, and how you restore your system. Your thoughts, feelings, and social connections even regulate your genes too. You can turn on genes that create health or disease or weight gain or weight loss.

In today’s episode, I talk with Drs. Jeff Bland, Bruce Lipton, and Todd LePine about how environmental and lifestyle factors are significant determining factors of your health.

Dr. Jeff Bland is the founder of Big Bold Health, a company on a mission to transform the way people think about one of nature’s greatest innovations—the immune system. Through Big Bold Health, Jeff is advocating for the power of immuno-rejuvenation to enhance immunity at a global level, often through the rediscovery of ancient food crops and superfoods. Jeff’s career in health spans more than 40 years. A nutritional biochemist by training, he began in academia as a university professor. Jeff then spent three decades in the natural products industry, working alongside other pioneers.

Dr. Bruce Lipton is a stem cell biologist and author of the bestselling books The Biology of Belief, Spontaneous Evolution, and The Honeymoon Effect. Dr. Lipton is the recipient of the prestigious Japanese Goi Peace Award and has been listed in “the 100 Most Spiritually Influential Living People” by Watkins Mind Body Spirit magazine for the last 13 years.

Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in internal medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body.

This episode is brought to you by Rupa Health, Sensate, and Super Simple Protein.

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Full-length episodes (and corresponding links) of these interviews can be found here:

Dr. Jeff Bland

Dr. Bruce Lipton

Dr. Todd LePine

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On this episode, I will go over the importance of vulnerability and how that will not only save you time, improve all your relationships, but also how learning to be more vulnerable will do wonder for your self love and self respect. Do not miss this one!

Science fact: Epigenetics

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Robert and Cody finish watching and discussing episode one of Jordan B. Peterson's new TV show. 

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Have you ever felt held back by a habit or pattern of thinking that you feel powerless to break? Or perhaps felt frustrated by a loved one’s failure to see mistakes they’re repeating? The reason it’s so hard, says today’s guest, is that these actions are programmed into our subconscious minds from early childhood. And they affect not just our behaviour but our whole experience of life and even our risk of disease. The chances are we’re completely unaware of these programs but, importantly, we can change them.

Dr Bruce Lipton began his career as a cell biologist graduating from the University of Virgina before joining the Department of Anatomy at the University of Wisconsin’s School of Medicine in 1973. Today, he describes his work as bridging science and spirituality and in his bestselling book The Biology of Belief, he sets out the idea that our thoughts affect all the cells in our body.

Bruce explains how, as children, our subconscious minds ‘download’ what we see and hear adults around us doing and saying – and these become the programs that drive our habits and thinking throughout life. Depending on our early experiences, they might be programs like ‘I’m not good enough’ or ‘It’s my fault’ – and it’s not much of a leap to see how these might create unwanted behaviours as we grow up.

Happily, we can cultivate self-awareness and learn to reprogram our minds, to create positive behaviour change. Bruce shares his practical guidance on how we can start to do that immediately. As we go on to discuss, reprogramming our minds can be incredibly liberating, affecting our happiness, confidence, health, work and relationships – with others and, crucially, with ourselves.

This was a warm and empowering conversation with a wonderful, kind-hearted man. I hope you enjoy listening.

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