obesity

Johann Hari is back on the podcast today and he looks completely different to the last time I saw him. He’s lost an incredible amount of weight, his face looks completely different and it’s all because of a drug you’ve probably already heard of. Ozempic.

Also known as GLP-1 agonists, these drugs were initially used by doctors like myself in General Practice for type 2 diabetics, but have now found a use case to treat obesity.

For over a year, Johann has been self treating with the drugs and diving into the history of how these drugs were discovered and utilised. From the lab to the pharmaceutical companies & the doctors surgery to the popular pages of celebrity gossip columns; Johann tells the full story without shying away from the potentially dangerous reality of the sideffects and risks of these popular medications.

We talk about:

What Ozepmic and similar drugs do to your brain and gut

How it impacts addiction to food and other substances

What the potential risks are including cancer, pancreatitis and bowel obstruction

Why UPF and obesity are the main concern

You can purchase Johann’s newest book, ‘Magic Pill: The Extraordinary Benefits and Disturbing Risks of the New Weight Loss Drugs’, available on 2nd May 2024, here: https://amzn.to/3Ulz2UB

Johann Hari is a New York Times best-selling author, his books include, ‘Chasing the Scream’, ‘Lost Connections’, and ‘Stolen Focus’. He has written for the world’s leading newspapers and magazines, and has twice been named ‘National Newspaper Journalist of the Year’ by Amnesty International.

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There are several different schools of thought behind obesity and metabolic dysfunction, for example, the energy balance model or “calories-in, calories-out” perspective that many people have felt fooled by. While calories certainly are one piece, there is much more to the puzzle of weight management and metabolic health, like hormonal cascades and oxidative stress.

My guest today is Dr. Robert Lustig, an author and neuroendocrinologist with expertise in metabolism, obesity, and nutrition. He has dedicated his retirement from clinical medicine to help fix the food supply in any way he can, to reduce human suffering, and to promote a collective vision of metabolic health: protect the liver, feed the gut, support the brain. 

In this episode we discuss:

• Is a calorie really just a calorie? (7:24)
• The surprising truth: All models of energy intake are a little right and a little wrong (9:20)
• Proven methods for reducing insulin to support weight loss (29:39)
• What are obesogens and how are they hijacking our metabolic health? (32:00)
• Reactive oxygen species and aging (and how to reduce them) (38:05)
• Why glucose and insulin monitoring are powerful levers for metabolic health (42:15)
• Summing up the facts and our beliefs around calories and weight (47:00)
• The cellular impact of oxidative stress and chronic stress (54:00)
• Monch Monch: a new fiber solution for absorbing simple sugars and preventing glucose spikes as well as increasing satiety and boosting microbial diversity (1:02:20)
• Food addiction in adults and children and addressing the root cause (1:10:45)
• What actions can we take based on scientific advances to make our lives better? (1:24:15)
• Why any food that feeds the gut, protects the liver, and supports the brain is a healthy food (1:33:35)
• Perfact and how to use it to understand what is metabolically healthy at your exact grocery store (1:40:20)

This episode is brought to you by Rupa Health, Pendulum, ARMRA Colostrum, and Wonderfeel. 

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Poor metabolic health is the largest underlying cause of early death worldwide, making it the canary in the coal mine for not just type 2 diabetes, but a multitude of illnesses such as Alzheimer’s, heart disease, cancer, obesity, and even some cases of infertility and depression. Sadly, many people are walking around without even knowing they need to address their metabolic health or have any idea how to do that.

In today’s episode, I talk with Dr. William Li, Dr. Casey Means, and Dr. Richard Johnson about why metabolic health is important and ways that we can start improving it immediately at home.

This episode is brought to you by Mitopure, Cozy Earth, and AG1.

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Ozempic, the injectable weight loss drug, is discussed by Calley Means and Robert F. Kennedy Jr is this short episode.

A second longer episode with Calley Means is coming soon. Please share and subscribe.

Calley Means is on a mission to steer more healthcare dollars to incentivize metabolic habits at the root of disease (healthy food, exercise, sleep, stress management).

This week's Addicted to Fitness focuses on the downside of a popular weight loss drug. Nick and Shannon discuss why the popularity of Ozempic for weight loss is causing the drug to be difficult to acquire by individuals with Type 2 diabetes, the potentially dangerous muscle loss side effect the drug causes, and the numerous health & wellness venues that are trying to benefit from the drug's popularity. Follow the podcast profile on Instagram @TheATFPodcast. Give it a listen and let us know what you think by leaving a rating & review in Apple Podcasts.

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Our hormones coordinate many different functions in our body and control everything from our metabolism to our sexual function, circadian rhythms, and mood. These chemical messengers also play a big role when it comes to our appetites.

In today’s episode of my series I’m calling Health Bites, I am talking about two lesser-known hormones, leptin and ghrelin, which you may not have heard of before but that have a direct impact on our body and health. 

This episode is brought to you by Mitopure, Rupa Health, and Seed.

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In this episode, I discuss (audio version / Apple Subscriber version):

• Why are so many people overweight? (3:29 / 1:36)
• What do leptin and ghrelin regulate in our bodies? (4:20 / 2:27)
• What happens when your leptin and ghrelin levels are out of whack? (6:27 / 4:35)
• Strategies to keep your leptin and ghrelin levels balanced and healthy (12:02 / 8:46)

Mentioned in this episode

The Fat Resistance Diet by Dr. Leo Galland

Force of Nature

FOOD: What the Heck Should I Eat?

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Robert F. Kennedy, Jr. is an independent candidate for President of the United States. He is the founder of the Waterkeeper Alliance—the world’s largest clean water advocacy group—and served as its longtime chairman and attorney. He founded the Children’s Health Defense, where he served as chairman and chief litigation counsel in its campaign to address childhood chronic disease and toxic exposures. He was also on the team that prosecuted and won the case against Monsanto for glyphosate's role in causing cancer.

As President, he promises to restore the middle class, unravel corporate capture, end the chronic disease epidemic, improve the quality of the water we drink and the air we breathe, heal the divide, fix our public education system, take care of our veterans, support the trades, make homes affordable again, support regenerative farming, among other key priorities.

This episode is brought to you by Rupa Health, Cozy Earth, Bioptimizers, and Fatty15.

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In this episode we discuss (audio version / Apple Subscriber version):

• The state of health in America (5:41 / 4:01)
• One of the main reasons RFK Jr. is running for president (8:39 / 6:59)
• The beginning of the autism epidemic (12:38 / 10:58)
• Addressing harms caused by ultra-processed food (15:03 / 13:23)
• Eliminating corporate culture in government agencies (33:05 / 28:41)
• America’s disproportionate deaths from COVID-19 (42:10 / 37:46)
• How America’s health status is affecting our national security (44:34 / 40:10)
• Solving the mental health crisis (47:41 / 43:17)
• Food and drug TV marketing (56:14 / 51:49)
• Bobby’s thinking about fitness for himself and America (1:03:39 / 59:14)

Enter for a chance to hike in LA with Bobby and me here.

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Certain cancer rates rise among younger Americans. We get the facts behind the figures from Dr. Otis Brawley, professor of Oncology and Epidemiology at Johns Hopkins University. Get the facts first on Morning Wire.

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In today’s episode of my series I’m calling Health Bites, I am tackling a topic that has left an indelible mark on the world: the COVID-19 pandemic. As we navigate through new variants and climbing cases, it's crucial to unravel the reasons why so many Americans got so sick and died during the pandemic. We dig into the questions of why we as a nation were so susceptible to COVID-19’s deadly effects. I also explore why and how Functional Medicine steps in where conventional approaches stumble.

This episode is brought to you by AG1, Rupa Health, and Seed.

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Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.

In this episode, I discuss (audio version / Apple Subscriber version):

• Why the U.S. had some of the worst COVID-19 outcomes (7:07 / 5:24)
• The conventional medicine approach to the COVID-19 pandemic (25:46 / 22:41)
• My take on COVID vaccines (28:30 / 25:25)
• Optimizing our immune system to prevent serious infection and disease (39:09 / 36:04)
• Preventing and recovering from illness using diet and lifestyle (47:19 / 44:14)
• Supplements to support your immune system during cold and flu season (57:00 / 53:55)
• Strategies for COVID infection and exposure (59:34 / 56:29)
• Long-COVID (1:02:51 / 59:46)

Connect with Dr. Mark Hyman on Twitter, Instagram, Facebook, and YouTube

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Why do we all eat stuff that isn’t food and why can’t we stop? In this episode, Dr Chris van Tulleken, author of Ultra-Processed People explains all. As well as being one of the UK’s leading science broadcasters, Chris is a practising infectious diseases doctor in the NHS. He gained his medical degree at Oxford University and his PhD in molecular virology from University College London, where he is an associate professor. He works closely with the World Health Organization and UNICEF, and his research looks at how corporations affect human health.

In this episode, Chris explores what may be the biggest public health crisis of our time: ultra-processed food, or UPF, for short. Many people these days, certainly most regular listeners to this podcast, will be aware of UPFs. But there’s still a lot of confusion around what they really are. For Chris, it’s simple: if it’s wrapped in plastic and has at least one ingredient you wouldn’t find in a home kitchen, it’s a UPF. If it makes a health claim on the packet? Ironically, it’s even more likely!

A UPF is any food that’s processed industrially and created for big-business profit, rather than to provide nutrients. And here in the UK, UPF makes up 60 percent of the average diet. The trouble is, says Chris, UPFs have been shown to be the leading cause of early death in the world, ahead of tobacco. Even if you remain at what is considered a healthy weight, consuming UPFs still leaves you vulnerable to things like Type 2 Diabetes, heart disease, dementia, anxiety, depression, inflammatory bowel disease, cancer and eating disorders.

In this conversation, Chris provides a clear definition of the difference between processing and ultra-processing, and explains how our toxic food environment is designed to be addictive. We also discuss a whole range of different topics such as the need to see obesity as a condition and not an identity and the seemingly revolutionary idea that re-prioritising food shopping and cooking as a vital, enjoyable part of our day, could be a first step towards the societal change that’s urgently needed.

This podcast episode is not about shame or blame - it’s about education and empowerment. Chris is a brilliant communicator who insists the prevalence and appeal of UPFs is not our fault. I thoroughly enjoyed my conversation with him - I hope you enjoy listening.

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DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

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Ozempic and other GLP-1 agonists like Wegovy have exploded as “miracle weight loss drugs.” But as the research unfolds, we’re quickly discovering that these drugs are not risk free and come with some very concerning side effects.

In today’s episode of my series I’m calling Health Bites, I dive deep into the complexities of Ozempic. From nationwide shortages, high costs, the lack of insurance coverage, and severe, somewhat common, side effects, I explore the hurdles of Ozempic and question if it's truly a sustainable solution to our growing obesity crisis. 

This episode is brought to you by Mitopure and Cozy Earth.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com and use code DRHYMAN.

Here are more details from the episode (audio version / Apple Subscriber version):

• Current and potential uses for Ozempic and GLP-1 (6:42 / 4:01)
• Common side effects from Ozempic (8:48 / 6:07)
• Understanding the obesity and chronic disease crisis (9:33 / 6:52)
• Long-term risks associated with Ozempic (14:47 / 12:06)
• Combatting the idea that obesity is genetic (17:54 / 15:13)
• Can you be healthy at any size? (20:37 / 17:55)
• How traditional medicine misses the mark in addressing obesity (24:36 / 21:55)
• Clinical research findings of Ozempic use (31:44 / 29:03)
• Addressing the root cause of obesity and type 2 diabetes (35:34 / 32:53)

Mentioned in this episode

Dr. Hyman’s Free Sleep Masterclass

Function Health

The 10-day Detox Diet

Connect with Dr. Mark Hyman on Twitter, Instagram, Facebook, and YouTube

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This episode is brought to you by Mitopure and LMNT.

For nearly all of our history, humans consumed no grains, and our bodies are designed to work very well without them. Today, however, grain-based foods are by far the number one source of calories in the American diet. While whole grains can be a great source of vitamins, minerals, and fiber, the toxic amounts we eat contribute to obesity, diabetes, heart disease, cancer, and dementia. Plus, most of the grains we eat—even whole wheat—are turned into flour products which have a higher glycemic index than table sugar.

In today’s episode of my series I’m calling Health Bites, I talk about why grains are such a contentious food, how to tackle the pros and cons of whether it belongs in your diet, and which grains are actually okay to eat. 

This episode is brought to you by Mitopure and LMNT.

Support the growth of new, healthy mitochondria and get 10% off Mitopure. Head to timelinenutrition.com/drmark and use code DRMARK at checkout.

Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/hyman today.

Here are more details from our interview (audio version / Apple Subscriber version):

• You don’t have to eat grains to be healthy (8:40 / 5:41)
• “Whole grain” is a marketing term (10:31 / 7:32)
• Why starch and sugar are essentially the same thing (11:22 / 8:23)
• You’re not eating the same grains your grandparents ate (11:58 / 8:59)
• Is oatmeal good for you? (14:22 / 11:23)
• Should everyone avoid gluten? (15:36 / 12:37)
• Not all grains are bad (20:02 / 17:03)
• Do we really have to give up bread? (21:09 / 18:10)
• What types of grains are okay and what should be avoided? (23:20 / 20:21)
• Who should avoid grains altogether? (24:59 / 22:00)

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