chronic disease

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Dr. Nir Barzilai is a geroscientist, Chaired Professor of Medicine and Genetics, and the founder and principal investigator of the Einstein Nathan Shock Center and the Glenn Center for Excellence in Biology of Aging. He also studies families of centenarians that have provided genetic and biological insights on the protection against aging—with several drugs developed based, in part, on these paradigm-changing studies. He is also leading the TAME (Targeting/Taming Aging with Metformin) trial to prove to the FDA that aging can be delayed and to allow for next-generation interventions. 

This episode is brought to you by Sunlighten, Cozy Earth, BiOptimizers, and Fatty 15.

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In this episode we discuss (audio version / Apple Subscriber version):

• The hallmarks of aging (9:01 / 7:10)
• What causes the hallmarks of aging? (15:40 / 13:49)
• Dr. Barzilai’s research on centenarians (23:16 / 21:25)
• Why living to 100+ years is good for the economy (24:54 / 23:03)
• What enables someone to live to 100 years old? (29:30 / 25:20)
• Taking growth hormone and Metformin have different effects based on your age (36:58 / 32:48)
• The connection between HDL cholesterol and longevity (43:36 / 39:26)
• Dr. Barzilai’s research on Metformin (56:23 / 52:13)
• How Metformin works in the body and on muscle growth (1:04:51 / 1:00:41)
• Dr. Barzilai’s personal longevity (1:42:05 / 1:37:55)

Learn more about the Longevity Genes Project and the TAME Trial. 

Get a copy of Age Later: Health Span, Life Span, and the New Science of Longevity

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This episode is brought to you by Rupa Health, Pendulum, Mitopure, and Thrive Market.

The world is facing several big challenges today—the climate crisis, food insecurity, racial injustice, the rise of AI, and insufficient access to healthcare, to name just a few. 

Today on The Doctor’s Farmacy, I am excited to talk to Dr. Rajiv Shah about how large-scale change really happens, the success and lessons he has learned throughout his career, and why we need big bets—large, bold actions—in order to solve the world’s greatest challenges.

Dr. Rajiv Shah serves as president of the Rockefeller Foundation, a global institution with a mission to promote the well-being of humanity around the world. With a century-long track record of leveraging science, technology, and innovation, The Foundation is pioneering new ways to enable individuals, families, and communities to flourish. Dr. Shah is a graduate of the University of Michigan, the University of Pennsylvania School of Medicine, and the Wharton School. He has received several honorary degrees, the Secretary of State’s Distinguished Service Award, and the US Global Leadership Award. He is married to Shivam Mallick Shah, and they have three children.

This episode is brought to you by Rupa Health, Pendulum, Mitopure, and Thrive Market.

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Here are more details from our interview (audio version / Apple Subscriber version):

• How Rajiv was inspired by Nelson Mandela in his youth (5:25 / 3:41)
• The first crisis Rajiv dealt with as the head of USAID (9:05 / 7:21)
• Tackling the chronic disease epidemic with food as medicine (14:54 / 13:09)
• Addressing rising obesity rates in America (32:31 / 27:52)
• The importance of believing change is possible (42:33 / 37:54)
• What makes the standard American diet so unhealthy? (48:42 / 
• Investing in weight-loss drugs vs quality food (49:26 / 44:03)
• The importance of finding the right partners to make meaningful change (52:13 / 47:35)
• Finding happiness through service to others (56:02 / 51:25)
• Rajiv’s next big bets (1:04:14 / 59:40)

Get a copy of Big Bets: How Large-Scale Change Really Happens.

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What do obesity, insulin resistance, diabetes, fatty liver disease, hypertension, cardiovascular disease, stroke and dementia have in common? They are all chronic diseases that together are the leading cause of death in the world today. And they’re largely caused not by genes, but by our environment, lifestyle and food choices.

This much many of us already know. But today’s guest brings some valuable new information to the table: the role of uric acid. Dr David Perlmutter is a board-certified neurologist and six-time New York Times bestselling author. He is on the Board of Directors of the American College of Nutrition and an Associate Professor at the University of Miami Miller School of Medicine. His latest book, Drop Acid: The Surprising New Science of Uric Acid, focuses on the pivotal role of uric acid in chronic metabolic diseases, claiming that lowering its level in the body holds the key to losing weight, controlling blood sugar, and transforming health.

Many of us only think about uric acid in relation to a painful condition called gout. But, as David explains even slightly raised uric acid levels, can have damaging and widespread implications for our health. David and I discuss what he calls the ‘evolutionary environmental mismatch’ - how modern lives are at odds with what serves our biology best. And one of the key elements that is driving this mismatch is the modern food environment.

Many of us simply think about food as energy or calories but David and I discuss why we need to start thinking about food as information. Every bite that we eat is giving our body cues and signals. If we give our bodies the right cues they will thrive. If we give them the wrong cues they will start to malfunction.

We also talk about the relationship between our fructose intake and uric acid levels, the evolutionary benefit for slightly higher uric acid levels, how increased uric acid can drive fat storage, high blood sugar levels, high blood pressure and insulin resistance. We also discuss what changes we can make with our food choices to reduce uric acid levels in our body.

David explains how certain food choices can make us more impulsive, less compassionate and less empathetic and how the right food choices can help us make better decisions and increase our happiness. David is a gifted communicator and someone who is committed to helping as many people as possible, live healthier and happier lives. I hope you enjoy listening.

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Show notes https://drchatterjee.com/368

DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

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In 2020, Bradley found himself questioning death. He was 24 and lying in hospital bed with bleeding lungs caused by his condition, cystic fibrosis. Three years later, he has run multiple marathons, left behind his successful career as a realtor and is now running his podcast 'A Lot To Talk About', sharing his story. This week we break down his journey, including his philosophy towards overcoming the adversity we all face in our 20s, whatever that may be. We dive into the psychology of living with a chronic disease and how Bradley's entire perspective has changed since 2020. Listen to his inspiring story and interview now. 

Bradley's podcast: https://open.spotify.com/show/0F7u8INlXQ0KvtjwK6Zf12?si=3bfe175327f94848

Follow Bradley on Instagram: https://www.instagram.com/bradleyjdryburgh/?hl=en

Follow us on Instagram: https://www.instagram.com/thatpsychologypodcast/?hl=en

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https://lewishowes.com/mindset - Order a copy of my new book The Greatness Mindset today!

Based in Seattle, Washington, Dr. Jeffrey Bland is a world-renowned nutritional medicine expert, “father of Functional Medicine”, and founder of Big Bold Health, a company on a mission to transform the way people think about one of nature’s greatest innovations — the immune system. 

Jeffrey is advocating for the power of Immuno-Rejuvenation to enhance immunity at a global level, often through the rediscovery of ancient food crops and superfoods. To get there, Jeffrey is building a network of small farms and suppliers throughout the US that take a clear stance on regenerative agriculture, environmental stewardship, and planetary health. Jeffrey’s career in health spans more than 40 years. 

Visit Big Bold Health and use code GREATNESS10 at checkout for 10% off.

In this episode you will learn,

• Valuable insights on how nutrition can strengthen the immune system and prevent chronic diseases.
• The importance of adopting a personalized approach to nutrition, considering factors such as genetics, lifestyle, and environmental influences.
• The role of specific nutrients, such as vitamins, minerals, and antioxidants, in supporting immune function and overall health.
• The significance of maintaining a balanced gut microbiome and shares practical tips for optimizing digestive health.
• Valuable knowledge and actionable strategies to enhance their immunity and promote long-term well-being through proper nutrition.

For more information go to www.lewishowes.com/1442

Casey Means: https://link.chtbl.com/1252-pod

Daniel Amen: https://link.chtbl.com/1243-pod

David Sinclair: https://link.chtbl.com/1232-pod

Dr. Fatima Cody Stanford believes obesity should be treated like any other disease.

This episode is brought to you by Rupa Health, InsideTracker, and Essentia.

Subsidizing food has been a practice in the US government for a very long time; we’ve subsidized sugar since 1790 and wheat, corn, and soy since 1933. All four of these foods, also known as commodity crops, are mainstay ingredients found in the ultra-processed foods driving chronic disease. And we taxpayers are footing the bill. Something is wrong with this picture.

In today’s episode, I talk with Dr. Robert Lustig, Ken Cook, and Paulette Jordan about the impact of subsidized commodity crops on food prices and our health.

Dr. Robert Lustig is a neuroendocrinologist with expertise in metabolism, obesity, and nutrition. He’s the Emeritus Professor of Pediatrics in the Division of Endocrinology and a member of the Institute for Health Policy Studies at UCSF. He is also one of the leaders of the current “anti-sugar” movement that is changing the food industry, in part through his game-changing books. His latest work is Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine.

Ken Cook is the president and cofounder of the Environmental Working Group (EWG). He is widely recognized as one of the environmental community’s most prominent and influential critics of industrial agriculture and the nation’s broken approach to protecting families and children from toxic substances. Under Cook’s leadership, the EWG has pioneered the use of digital technologies to empower American families with easy-to-use, science-driven tools to help reduce their exposure to potentially harmful ingredients in food, drinking water, cosmetics, and other household products.

Paulette Jordan was the 2018 Democratic gubernatorial nominee in Idaho, becoming the first woman nominated to the position by a major party in the state and the first Native American woman nominated for governor in US history. She is recognized in Idaho and across the nation as an inspirational and audacious leader.

This episode is brought to you by Rupa Health, InsideTracker, and Essentia. 

Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman.

Right now you can get an extra $100 off your mattress purchase, on top of Essentia’s Black Friday sale, the biggest sale of the year, which will also take 25% OFF your mattress purchase. Go to myessentia.com/drmarkhyman to learn more.

Full-length episodes of these interviews can be found here:

Dr. Robert Lustig

Ken Cook

Paulette Jordan

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// R E A D Y • S E T • R E S E T

In this thought leader episode, we dive into how we can create an even playing field for people in our country regarding healthcare.

Marianne Williamson is a bestselling author, non-profit and political activist, and spiritual thought leader. For over three decades, Marianne has been a leader in spiritual and religiously progressive circles. She is the author of 14 books, four of which have been #1 New York Times bestsellers. A quote from the mega-bestseller A Return to Love, “Our deepest fear is not that we are inadequate. Our deepest fear is that we are powerful beyond measure…” is considered an anthem for a contemporary generation of seekers.                                                                               

In this podcast, we cover:

• How getting money out of politics will pave the path to healthcare sustainability
• Why you have to be wealthy to be healthy in America
• The importance of facing the root causes rather than the symptoms
• How we can have more open conversations about the healthcare industry
• What we should do to get rid of the pandemic in America

// E P I S O D E   S P O N S O R S 

• Pre-Order a copy of The Menopause Reset book today and get the bonus ebook now, for FREE!

// R E S O U R C E S   M E N T I O N E D

• Podcast
• The course of Miracles Daily Lessons
• Marianne Website
• Book: The Politics of Love
• Marianne Instagram
• Marianne Facebook

// F O L L O W

• Instagram | @dr.mindypelz & @theresetterpodcast
• Facebook | /drmindypelz & /theresetterpodcast
• Youtube | /drmindypelz

Please note the following medical disclaimer: By listening to this podcast you understand that this video is for educational purposes only. It is not intended to substitute for professional medical advice and should not be relied on as health or personal advice. Always seek the guidance of your doctor with any questions you may have regarding your health or medical condition.  

Modern scientists have extensively researched addicts and the things they abuse, but we still don't understand everything about the nature of addiction. So how does it work? Tune in to learn more about addiction (and why you can't kick your SYSK habit).

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