mdma

Rick Doblin, Ph.D., is the Founder in 1986 and President of the Multidisciplinary Association for Psychedelic Studies (MAPS), a nonprofit that wholly owns its pharmaceutical arm, MAPS Public Benefit Corporation (PBC), which has completed two highly successful Phase 3 studies of MDMA-assisted therapy for PTSD. MAPS PBC stands at a crossroads between obtaining the additional resources it needs from philanthropy, ensuring public benefit is foremost, or becoming a publicly traded company. 

maps.org

In just a few years, psychedelics have gone from being a symbol of the 1960s counterculture to being touted as highly promising mental health treatments. Dr. Albert Garcia-Romeu, PhD, of Johns Hopkins University, talks about whether the research backs up the hype; the state of psychedelic therapy research for PTSD, depression, addiction and other mental health disorders; how psychedelics work in the brain and mind; and whether psychedelic treatments are likely to be approved in the U.S. any time soon.

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Sam Harris speaks with Roland Griffiths about psychedelics and mortality. They discuss the current state of psychedelic research, the timeline for FDA approvals, the risks to mental health posed by psychedelics in vulnerable populations, the use of psychedelics among the well, the relationship between psychedelics and meditation, advice for “bad” trips, microdosing, Roland’s stage-4 cancer diagnosis, reflections on death, and other topics.

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Learning how to train your mind is the single greatest investment you can make in life. That’s why Sam Harris created the Waking Up app. From rational mindfulness practice to lessons on some of life’s most important topics, join Sam as he demystifies the practice of meditation and explores the theory behind it.

Today I am joined by the incredible Sarah Reid, CEO of Minds I Health Solutions and Clinical Researcher. This week we are discussing healing racial and generational trauma through psychedelic assisted therapy. Sarah was the first black therapist to provide MDMA-assisted psychotherapy in a clinical trial and today she shares with us her first hand experience working with these life changing modalities. 

In this episode, I share: 

• How Sarah became involved in psychedelic studies
• MDMA and Ketamine therapies
• The spirit in therapy sessions and how we can work with it
• Mental health advocacy in underserved American communities
• Functional PTSD and race based trauma in society 
• Changing the way we talk about mental health to take our power back
• Using Psychedelics as a tool to help resolve trauma stored in the body
• What the potential impact of Covid 19 could have on mental health going forward
• What common threads Sarah has noticed through her experience with psychotherapies
• The effectiveness of psychedelics in psychotherapy
• Amazing personal stories of change in participants with trauma and PTSD
• The use of music and how it can be used to heal along with these therapies

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Rick Doblin is the founder and Executive Director of the non-profit psychedelic research and educational organization, the Multidisciplinary Association for Psychedelic Studies (MAPS). http://maps.org/join

Three leading researchers from the Mount Sinai Health System discuss how ketamine, cannabis, and ecstasy are being used (or studied) to treat everything from severe depression to addiction to PTSD. We discuss the upsides, downsides, and regulatory puzzles.

The Psychedelic News Hour | | Brought to you by How to Lead: Wisdom from the World's Greatest CEOs, Founders, and Game Changers by David M. Rubenstein

Welcome to another episode of The Tim Ferriss Show, where it is normally my job to deconstruct world-class performers of various types, of all ilks. 

In this special episode, the tables are turned. Instead of interviewing someone else, I am interviewed by two experts on several topics I’ve both studied and supported, including psychedelic-assisted psychotherapy and what it can do to heal trauma and—broadly speaking—possible futures for mental health. This audio was recorded on a new show, The Psychedelic News Hour, soon to be a podcast, and I’m in conversation with two people: David Rabin, MD, PhD, (@drdavidrabin), a board-certified psychiatrist and neuroscientist, executive director of The Board of Medicine, and co-founder of Apollo Neuroscience, and Molly Maloof, MD, (@drmolly.co), a physician, Stanford lecturer, and ketamine-assisted psychotherapist.

This episode was recorded on Clubhouse, an app still in private beta and defined by their tagline: “Clubhouse is a space for casual, drop-in audio conversations—with friends and other interesting people around the world.” 

One final note: I recorded this on my phone, a necessity for using the app, so the audio quality isn’t studio quality, but it was polished as much as possible. Thank you for understanding, and thanks to everyone who joined and asked thoughtful questions. 

This episode is brought to you by the book How to Lead by David Rubenstein. David Rubenstein is one of the visionary founders of The Carlyle Group and host of The David Rubenstein Show, where he speaks to leaders from every walk of life about who they are, how they define "success," and what it means to lead. Jeff Bezos, Richard Branson, Warren Buffet, Bill Gates, Ruth Bader Ginsburg, Phil Knight, Oprah — all of them and more — are featured in his new book, titled How to Lead. This comprehensive leadership playbook illustrates the principles and guiding philosophies of the world’s greatest game-changers. In its pages, you can discover the experts’ secrets to being effective and innovative leaders. 

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Psychedelics have gotten very popular in the past few years for their therapeutic properties, but how much do you know about them? In this episode, I am going to talk about MDMA, which has a better success rate for PTSD than anything... ever! If all goes well with the FDA trials, MDMA could be legal to take with a therapist in the next 6-12 months.

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In this episode, Rick Doblin, founder and executive director of MAPS, discusses MDMA, a molecule that has (at a minimum) revolutionary therapeutic benefits for PTSD, but arguably could have, at the highest order, a lasting impact on humanity’s ability to peacefully coexist. Rick details the history of MDMA, what lead to its unfortunate criminalization, and his lifelong work trying to protect MDMA (and other psychedelics) from criminalization (and his subsequent attempt to decriminalize it). Through his founding of MAPS, Rick has made enormous progress in debunking many of the exaggerated risks being claimed against MDMA (neurotoxicity, memory loss, depression, Parkinson’s, etc.), and is very close to getting FDA approval for a psychotherapy technique using MDMA. Additionally, in this discussion, you will learn about the history of LSD, psilocybin, and other psychedelics and how the combination of the misunderstanding of them with the crackdown on drug use in the 1970s lead to their designation of schedule 1 substances. But it’s important to note that you will also realize from this discussion just how different MDMA is compared to the average psychedelic. We end this discussion with a message of hope: there are going to be many people who are going to wonder what can they do to receive this MDMA therapy. We talk about what those clinical trials look like, what the enrollment looks like, and perhaps more importantly, what a compassionate use license would look like, such that if there are patients who are in need of this therapy (prior to its approval) they can have an understanding of the legal paths to doing just that.

We discuss:

• Discovering MDMA, how Rick learned about it and his first experiences with it [9:45];
  
• The timeline of MDMA’s evolution, the reinvention in the 1970s, “ecstasy”, the criminalization of MDMA [21:10];
  
• Explaining the different “schedules” of drugs [30:55];
  
• Rick’s fight to protect it for therapeutic uses, losing to the DEA despite winning in the court, the scientific community, and the media [38:25];
  
• The risks involved with taking MDMA [42:30];
  
• An incredible MDMA-LSD case study: Rick’s story of healing a treatment-resistant PTSD patient in the 1980s [44:45];
  
• How and why MDMA was declared illegal on an emergency basis going against the judge’s recommendation after hearing Rick’s compelling case (and multiple appeals) in court [57:15];
  
• Rick’s decision to study politics to affect change from the inside out, and the recent progress being made with the DEA [1:07:00];
  
• Debunking the exaggerated risks of MDMA (e.g., neurotoxicity) [1:16:30];
  
• Rick’s unbelievable ability to play the long game [1:28:45];
  
• Which patients would not be good candidates for MDMA from a safety perspective? [1:34:30];
  
• How MDMA is different from all other psychedelics, the importance of the setting, and Peter’s experiences with MDMA [1:36:30];
  
• MDMA studies which lead to the crucial designation as a “breakthrough therapy” [1:40:30];
  
• How someone with PTSD can get treated now through “expanded access for compassionate use” [1:46:00];
  
• Rick’s ultimate goal and long term vision for psychedelic clinics [1:50:30];
• Trip of Compassion documentary, and how psychedelics could change the world [1:52:30];
  
• Rick’s early life: Resisting the draft, his feeling of wanting to change the world, and his profound experiences with LSD and other psychedelics [1:55:30];
  
• The history of LSD and psilocybin, and the CIA’s interest in psychedelics [2:10:45];
  
• Timothy Leary and the Good Friday Experiment [2:22:00];
  
• Rick’s follow up study to the Good Friday Experiment, and his criticism (and praise) of Tim Leary [2:33:50];
  
• Peter’s experience taking psilocybin [2:44:30];
  
• The Concord Prison Experiment, and Rick’s follow up study 34 years later [2:47:00]; and
  
• More.
  

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Some of you have tried the ecstasy. Others have merely heard about the drug on a TV sitcom, or heard about it in a news report. Either way, MDMA's power resonates through our culture -- and sometimes it's hard to distinguish the truth form the misinformation. But what exactly is this psychoactive agent? Where does it come from and what sort of effect does it have on the human experience? Join Robert and Christian as they explore the origins and properties of MDMA. (Originally published Dec. 17, 2015)

See omnystudio.com/listener for privacy information.

Some of you have tried the ecstasy. Others have merely heard about the drug on a TV sitcom, or heard about it in a news report. Either way, MDMA's power resonates through our culture -- and sometimes it's hard to distinguish the truth form the misinformation. But what exactly is this psychoactive agent? Where does it come from and what sort of effect does it have on the human experience? Join Robert and Christian as they explore the origins and properties of MDMA. (Originally published Dec. 15, 2015)

See omnystudio.com/listener for privacy information.