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    Maximizing Productivity, Physical & Mental Health with Daily Tools

    enJuly 12, 2021

    Podcast Summary

    • Optimizing productivity through science-based protocolsUnderstanding the body's natural clock and following protocols such as tracking wake-up times and temperature minimums can improve sleep and reduce anxiety, leading to increased productivity.

      The coordination of the earth's rotation and the human biology is not a coincidence. Managing the day as a unit can be optimized by leveraging science-based protocols. Knowing the temperature minimum, or the time when the body temperature is at its lowest point during the 24-hour cycle, is valuable and can help shift the circadian sleep schedule and eating schedule. Taking a walk or experiencing visual flow has a powerful effect on reducing anxiety by lowering the amygdala's neural activity. Knowing the average wake-up time and tracking it can help determine the temperature minimum. The information presented is backed by quality peer-reviewed science published in excellent journals.

    • The Benefits of Morning Walk for Optic Flow and Well-beingMorning walks can improve mental and physical well-being by reducing amygdala activation through optic flow generated by forward ambulation and lateral eye movements, as well as adequate stimulation of melanopsin intrinsically photosensitive ganglion cells in the eye.

      Taking a morning walk is not just about exercise, but also about getting into optic flow and reducing the levels of amygdala activation. Optic flow, generated by forward ambulation and lateral eye movements, reduces activity levels in the fear/anxiety center of the brain. Getting sunlight in your eyes, ideally outdoors and without sunglasses, is also crucial for mental and physical well-being. Adequate stimulation of the melanopsin intrinsically photosensitive ganglion cells in the eye sets in motion a cascade of biological processes in every cell and organ of your body. Walking outdoors for at least 10 minutes can ensure this stimulation and set you on the path to being alert and focused, but not anxious.

    • The benefits of natural morning sunlight exposure for overall wellbeingNatural sunlight exposure in the morning can improve cortisol levels for wakefulness and a healthy immune system. Walking outside and providing natural light for pets can also positively impact mental and physical health. Cost-effective alternatives to expensive alarm lights are available.

      Exposure to natural morning sunlight is important for healthy cortisol levels, which promote wakefulness and a healthy immune system. Bright light above or in front of you can boost alertness, while eliminating light exposure can promote sleepiness. Blue light is optimal for setting circadian rhythms, so blocking it during the day can have detrimental consequences. Taking a morning walk outdoors, ideally in natural sunlight, can boost both physical and mental health. Pet animals also need exposure to natural light and circadian rhythms. Buying expensive dawn alarm lights is unnecessary; a cheap light pad can provide sufficient brightness for light exposure. These simple protocols are cost-effective and easy to implement in daily routines, promoting overall wellbeing.

    • Simple Habits for Better Sleep, Mental Performance, and Caffeine ConsumptionLimiting exposure to bright light at night, staying hydrated with sea salt, and delaying caffeine intake can promote better sleep, improved cognitive function, and prevent caffeine crashes.

      Limiting exposure to bright light in the late evening and at night can help set the brain and body up for sleep better than just wearing blue light blockers. Hydration is essential for mental performance, and a little bit of sea salt in the water can help neurons function better. Delaying caffeine intake by 90 minutes to two hours after waking up can prevent a potential caffeine crash later in the day.

    • Optimizing Focus and Wakefulness through Delayed Caffeine Intake and Fasting.Delay caffeine intake and fast until mid-day for better focus and wakefulness. Andrew Huberman suggests caffeine and athletic greens for ingestion compatibility. Fasting leads to higher adrenaline levels, better focus, and learning. Blood sugar sensitivity determines what breaks the fast. Caffeine in teas releases GLP one for fat burning and treating diabetes and obesity.

      Delaying caffeine intake and fasting until mid-day can optimize wakefulness and focus. Caffeine and athletic greens (compatible with fasting) are Andrew Huberman's preferred sources of ingestion. Fasting increases adrenaline levels in the body, leading to better learning and focus. The sensitivity of blood sugar determines whether certain foods break a fast or not. Caffeine in teas leads to the release of GLP one, which increases fat burning and is being used to treat diabetes and obesity.

    • Optimize Your Workstation and Improve Alertness with Simple Tips and Yerba Monta DrinkKeep your screen at eye level for optimal attention and alertness. Yerba Monta is a biochemically proven approach to increase alertness and burn body fat. Use a strainer to extend tea leaves life and enjoy more benefits.

      Optimizing your workstation by keeping the screen at eye level or slightly higher can promote heightened states of alertness and optimal attention. Looking upwards creates a state of heightened alertness and helps support your levels of alertness. However, looking down and hooding your eyelids tends to decrease your levels of alertness and increase sleepiness. Yerba Monta is an affordable drink that increases GLP one, alertness, and helps in burning body fat, making it a biochemically rational approach. Using a strainer can extend the life of your tea leaves. Subsequent pouring over enhances the GLP one-stimulating aspects of the drink, releasing more of some of its beneficial compounds.

    • Tips to Improve Alertness and Productivity During WorkAdjust your posture and eye level, set up a distraction-free workspace, work for 90 minutes at a stretch, take short breaks, and manage your time wisely to stay focused and productive at work.

      Adjusting your body posture, eye position, and making use of timer feature can significantly increase your alertness and productivity during work. Setting up a workstation or a position that aligns with your eye level and helps improve alertness can help you avoid distractions. Research suggests that working for 90 minutes at a stretch can significantly boost your focus and productivity. To stay focused and motivated, try a program that locks you out of the internet or avoid distractions like phone calls or doorbells during work hours. While taking short breaks is necessary, resisting the urge to use the restroom can help boost alertness. Overall, being mindful of your body posture, eye position, and time management can significantly boost your productivity and work quality.

    • How to Optimize Productivity with a 90-Minute Work BlockFind your temperature minimum, create a focused work environment with low-level white noise and proper positioning of computer, eyes, and standing. Prioritize this block, avoid distractions, and reap the benefits of dopamine and norepinephrine release for increased satisfaction and accomplishment.

      One can optimize their productivity by creating a 90 minute block of work that is geared towards putting them in a tunnel of work, backed by low-level white noise and positioning of computer, eyes, and standing. This can be achieved by finding the best time of day to do the work using their temperature minimum, which is the time when their temperature is the lowest. This time can be found by adding 5-6 hours to the time when they wake up. Doing this work session consistently can lead to release of neuromodulators dopamine and norepinephrine, which contributes to a sense of accomplishment and satisfaction after completion. It is important to prioritize this work session and maintain focus, while avoiding distractions from social media or other sources.

    • Optimizing Focus and Productivity through ExerciseTo maximize the benefits of exercise, aim to work out during the rising phase of your body temperature. Incorporate both strength and endurance training five times per week and take two full days off for best results.

      To optimize focus and productivity, it's important to work out during the rising phase of your body temperature, which is influenced by your circadian rhythm. For those who wake up at 8:00 AM, starting a workout at 10:00 or 11:00 AM can be beneficial. After a 90 minute bout of cognitive work, doing physical exercise (especially strength and endurance work) for about an hour can support brain and overall health. Workouts should be kept relatively short and consistent, with at least five workouts per week and a 3-to-2 ratio between strength/hypertrophy and endurance work. Taking two full days off per week can also be beneficial for exercise performance and enjoyment.

    • The Crucial Connection between Exercise and Brain HealthA combination of endurance and resistance training with a focus on building capillary beds is ideal for overall health and optimal brain function. Prioritize resistance training for 10-12 weeks and switch to endurance training, with a workout duration of 60 minutes and intensity of 80% less than failure.

      A combination of endurance training and resistance training is crucial for overall health, including brain health. After 10-12 weeks of prioritizing resistance training, switch over to endurance training. Resistance training stimulates the release of hormones that positively impact brain function. Movement of various kinds is important for brain function as it receives its fuel by way of vasculature of blood vessels and capillaries. The optimal workout duration is about 60 minutes plus or minus 15 minutes. Endurance work should focus on building up capillary beds within the muscles to improve brain metabolism and cardiovascular function. Approximately 80% of workout intensity should be less than failure, with the remaining 20% at a higher intensity.

    • The Rational and Grounded Approach to Physical TrainingAlternating endurance and resistance training in a 3:2 ratio with an 80-20 split leads to improved health benefits. Ingesting electrolytes before fasted workouts aids mental clarity, while magnesium malate reduces muscle soreness. Training fasted boosts overall health.

      A rational and grounded protocol for physical training involves a three to two ratio, with three workouts per week on endurance work and two workouts on resistance training in alternating blocks. This split should have an 80-20 ratio, where 80% of the work is not to failure and 20% is, leading to improvements in lactate, metabolism, brain health, cardiovascular health, and oxygen utilization. For fasted workouts, ingesting water with electrolytes (sodium, magnesium, and potassium) can help neurons function correctly, quell hunger, and increase mental clarity. Magnesium malate can be used to offset delayed onset muscle soreness without causing drowsiness like other forms of magnesium. Training fasted can amplify exercise effects for increased cellular, liver, and organ health.

    • The Impact of Stimulants and Food Choices on AlertnessNon-stimulant alternatives like alpha GPC can improve cognitive performance while consuming high volumes of food, particularly carbohydrates, can lead to lethargy. Food choices based on scientific literature can support alertness.

      Stimulants like caffeine can aid motivation and fat metabolism during physical training but can have negative effects. Use non-stimulant alternatives like alpha GPC to improve cognitive performance. Eating large volumes of anything diverts blood to the gut, resulting in lethargy and less blood to the brain. Consuming protein, healthy fats, and lowish carbohydrates or no carbohydrates after fasting can support alertness throughout the day. Meats, nuts, and vegetables aid alertness, while carbohydrates tend to lend themselves to a state of sleepiness. Individuals have genes that allow them to eat large amounts of carbohydrate without suffering from lethargy. Food choices should be grounded in scientific literature related to alertness.

    • Omega-3 Fatty Acids and Other Nutrients for Optimal Brain HealthConsuming sufficient levels of omega-3 fatty acids can improve mood and act as an antidepressant. Eating a balanced diet, timing meals, and ensuring sufficient intake of selenium and cholesterol can also impact brain health.

      Ingesting sufficient levels of omega-3 fatty acids can improve mood and can act as an antidepressant, as shown by multiple studies. Consuming at least 1000 milligrams per day of the EPA form of essential fatty acid is as effective as prescription antidepressants in relieving depression. This allows people to take lower doses of those drugs, which have side effect profiles. People who regularly consume fatty salmon, krill, or foods that have a lot of omega-threes may not need to supplement with omega-3. The content and ratios of protein to fat to carbohydrates in food impact brain health. Timing and fasting periods are also beneficial for brain and body health. Sufficient selenium is important for proper thyroid production, which has an impact on brain metabolism. Cholesterol is necessary for hormone production, which can be problematic for brain and body health if insufficient.

    • The importance of Butter, Tongkat Ali, Forskolin, Light, and Science-supported protocols for greater vitality.Regular intake of good cholesterol such as Butter, taking Tongkat Ali and Forskolin, exposed morning and outside light for various organs and tissues, and implementing science-based protocols, can lead to better sleep, physical and mental performance, and reduced anxiety.

      Butter contains cholesterol which is a precursor to sex steroid hormones testosterone and estrogen. Sufficient levels of testosterone and estrogen are important for brain function and maintaining longevity. Tongkat Ali and Forskolin are compounds that increase free testosterone levels. Taking a brief walk post the mid-day meal accelerates metabolism and enhances nutrient utilization. Light is the primary Zeitgeber that tells the body what function should be turned on or off. Therefore, getting morning and outside light exposure is beneficial for various organs and tissues of the body. Implementing science-supported protocols can enhance sleep, physical, and mental performance, and reduce anxiety.

    • The Benefits of Hypnosis for Non-Sleep Deep RestHypnosis is a unique protocol in Non-Sleep Deep Rest that allows you to guide your brain towards a particular outcome or change. Reverie.com offers a zero-cost app with scientifically researched hypnosis protocols to enhance focus, creativity, reduce pain, anxiety, and improve sleep.

      Non sleep deep rest or MSDR is an umbrella term that includes protocols like meditation, yoga, nidra, and hypnosis that help to support better brain and body function. These protocols involve a deliberate and directed shift towards a state of deep relaxation, which has been shown by ample literature to be beneficial. Among these protocols, hypnosis, unlike naps or yoga nidra, is unique because it is very directed, allowing you to guide your brain towards a particular outcome or change. Reverie.com is a zero-cost hypnosis app that provides multiple hypnosis protocols, all backed by high-quality scientific research, to enhance focus, creativity, reduce pain, anxiety, and improve sleep. Hypnosis can increase plasticity, opening up pathways that allow you to change your brain in the ways that you want.

    • Strategies for optimal health and well-being through hypnosis, hydration, and exercise.Utilize hypnosis, hydration, and exercise to improve focus, sleep, and overall health. Limit naps to 90 minutes or less, and avoid bright light before bedtime. Implement personalized protocols to establish better sleep patterns and circadian rhythms.

      Hypnosis can be an effective zero-cost tool for improving focus, sleep, and overall health. Hydration and exercise, along with the proper use of caffeine, can also contribute to sustained energy throughout the day. Naps should be limited to 90 minutes or less and may interfere with sleep for some people. Exposure to afternoon light can offset disruption of sleep and other bodily functions caused by bright light later in the evening. Implementing these protocols can lead to better sleep health, wakefulness, metabolism and hormone health, and general well-being. It is important to adapt these protocols to individual needs and preferences, taking into account variations in sleep patterns and circadian rhythms.

    • Simple Habits for Better Sleep and MoodGet natural sunlight in the evening without sunglasses to regulate melatonin levels and eat starchy complex carbohydrates for better sleep and serotonin boost. Focus on simple lifestyle habits to optimize neurology and biology.

      To buffer against negative effects of bright light at night, lower your retina's sensitivity by following the simple protocol of getting sunlight for 5-30 minutes in the evening hours without sunglasses. This helps maintain appropriate levels of the sleep hormone, melatonin, which can be disrupted by light. Dinner comprising of starchy carbohydrates can support rest and deep sleep by increasing serotonin levels. It is important to distinguish between refined sugars and complex carbohydrates, as refined sugars can trigger sugar cravings and disrupt metabolism. Simple lifestyle habits such as getting natural light and eating healthy foods can optimize our neurology and biology, resulting in overall better mood, better learning, and better sleep.

    • Carb cycling for better sleep and cognitive functionCarb cycle for optimal cognitive function by fasting and consuming low/no carb diets for alertness, and starchy carbs for relaxation. Enhance sleep with hot baths/showers/saunas to lower body temperature.

      Carbohydrates can enhance the amount of serotonin in the brain, which is necessary for a good night's sleep. But supplementing serotonin directly can cause problems in the architecture of sleep that can last for several days. Low carbohydrates throughout the 24-hour period may not be attractive to most people, as it can affect cognitive function. Instead, creating a situation of fasting and then low-carb or no-carb diets for alertness and focus at one portion of the day and ingesting starchy carbohydrates for relaxation is a scientifically rational-based protocol. To enhance the transition to sleep safely, hot baths, hot showers, or saunas can accelerate the drop in temperature necessary for falling asleep easily and of sufficient duration and quality.

    • How Sauna and Sleep Affect Hormones and Muscle GrowthSauna sessions followed by cooling off periods can promote growth hormone secretion, essential for muscle growth. Optimal sleep environment with cool and dark room and use of safe compounds aids in transition to sleep. Consult with a doctor before taking supplements.

      Spending 20 minutes in the sauna and cooling off for 10 minutes before getting back in can lead to an increase in growth hormone, which is essential for muscle growth, metabolism, and tissue repair. To improve sleep, keep the room dark and cool so that you can move around and cool off as needed. Exposing palms, face, and feet to cool air is an efficient way to bring down body temperature. Although melatonin can aid in sleep transition, it may have negative effects on testosterone and estrogen levels and may suppress puberty onset. Magnesium, apigenin, and theanine are safer compounds that can aid in transition to sleep. Consult a physician before taking any supplements.

    • The Power of Magnesium and Natural Supplements for Better Sleep QualityUsing magnesium threonate and glycinate with natural supplements like apigenin and theanine can lead to better sleep quality and have neuroprotective effects, without the negative side effects of prescription drugs. However, individuals with gastrointestinal issues should avoid magnesium. Start winding down earlier to prevent middle-of-the-night waking.

      Magnesium threonate and glycinate can promote the release of GABA that inhibits the brain's forebrain leading to better sleep quality. Apigenin and Theanine in combination with magnesium can act as an effective sleep cocktail that helps people to fall asleep quickly. The combination can be beneficial as they carry lesser side effects than prescription drugs. However, some people may experience gastrointestinal discomfort from magnesium and should avoid it. Magnesium threonate and glycinate, besides aiding the transition to sleep, also have neuroprotective effects. Going to bed earlier can offset waking up in the middle of the night due to the early initiation of melatonin pulse and fighting it off by staying awake.

    • Tips for improving sleep quality and maintaining overall healthAvoid bright lights at night, try deep rest activities, establish a regular sleep schedule, take breaks and rest, and wake up at a consistent time even if staying up late. Prioritize healthy habits for a better quality of life.

      To improve sleep quality, avoid exposure to bright light during nighttime and engage in non-sleep deep rest activities like yoga nidra, sleep hypnosis and long exhale breathing to calm the mind. Establishing a consistent sleep schedule with regular wake-up and bedtimes also helps in maintaining circadian rhythms and improving overall health. While it's important to prioritize work and exercise, it's also necessary to take breaks and rest. Taking a day off per week to recover and do activities that promote enjoyment of life is beneficial. Even if staying up late, it's recommended to wake up at the regular time the next day and maintain a consistent sleep routine.

    • Optimize Your Daily Routine for Maximum ProductivitySchedule focused work blocks, prioritize quality sleep, and utilize science-backed methods to improve productivity and achieve deep work sessions consistently.

      To maximize productivity, try to have at least one or two 90-minute work blocks each day with no distractions, preferably in the morning. Combine these focused work sessions with other daily tasks and adapt them to your own schedule and job. Follow a consistent sleep schedule and avoid going to bed too early or too late. Use the power of science-backed methods to optimize your daily routine, such as getting morning light exposure and avoiding electronic devices before bed to improve sleep quality. Deep work sessions may differ depending on your job, but try to find a center of mass for your specific field and work with it. Remember that a few hours of dedicated, focused work each day can greatly improve productivity.

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    In this episode, I discuss skin health appearance and why both are important indicators of the health status of your immune system, gut microbiome, and other organ systems. I explain why sunlight is essential for skin and hormone health and how excessive sunlight can accelerate skin aging and cause certain skin cancers. I discuss the different types of sunscreens (physical, chemical, and mineral-based) and potential health concerns of the chemicals found in some (but not all) sunscreens. I also discuss the importance of getting your skin (and not just moles) checked for pre-cancerous and cancer growths, the role of nutrition and lifestyle factors that improve skin health and appearance, and how to improve your skin by reducing local and systemic inflammation and supporting your microbiome.  I explain what works to improve your skin's youthfulness and appearance, including reducing wrinkles, sagging, and pore size. I review the data on ingesting (or topically applied) collagen, vitamin C, niacinamide, hyaluronic acid, and retinol, and what is known about the use of peptides (e.g., BPC-157, copper peptides) and red and far-red light phototherapies for improving skin health and appearance. I also discuss the causes of acne, rosacea, and psoriasis and explain nutritional, skin care, and prescription-based approaches to treating these common skin conditions. This episode ought to help everyone better understand the biology of the skin and help them make the best possible decisions for their skin health, care, and appearance according to age, goals, and current skin conditions. Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com. Andrew's New Book Protocols: An Operating Manual for the Human Body: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman  ROKA: https://roka.com/huberman  LMNT: https://drinklmnt.com/huberman  Timestamps 00:00:00 Skin Health 00:02:59 Sponsors: Joovv, BetterHelp & ROKA  00:07:18 Skin Biology, Skin Layers 00:12:40 Sun Exposure, UV Light & Skin Cancers; Sunscreen 00:19:51 Aging, Sun Exposure, Skin Cancers, Physical Barriers 00:27:24 Sunburn & Skin Cancers 00:30:09 Sponsor: AG1 00:31:58 Vitamin D, Sun Exposure & Sunscreen 00:36:50 Organic (Chemical) Sunscreen & Inorganic (Mineral-Based) Sunscreen 00:49:20 Skin Cancers, Moles, Laser Resurfacing 00:53:59 Sponsor: LMNT 00:55:34 Sun Exposure, Melanoma & Life Expectancy 01:03:13 Tool: Youthful Skin, Collagen & Vitamin C 01:12:55 Peptides, BPC-157, Copper 01:20:58 Tool: Niacinamide (Nicotinamide), Youthful Skin, Dark Spots, Hyaluronic Acid 01:26:25 Tool: Retinol (Retin-A, Tretinoin, Retinyl Esters), Youthful Skin 01:33:07 Tool: Phototherapy, Youthful Skin, Treating Skin Conditions 01:41:10 Tool: Nutrition for Skin Health, Anti-Inflammatory Diets 01:47:54 Highly Processed Foods, Advanced Glycation End Products & Skin Health 01:52:08 Tools: Reduce Inflammation: Gut Microbiome, Sleep, Alcohol, Smoking, Stress 01:58:58 Acne, Hormones & Insulin; Tool: Low Glycemic Diet, Dairy 02:07:26 Tools: Face Cleansing & Acne; Scarring & Popping Pimples 02:13:29 Tool: Treating Rosacea, Alcohol, Skin Care, Nutrition 02:18:31 Stubborn Rosacea, Over Cleansing, Pulsed Dye Laser 02:21:04 Psoriasis Treatment, Immune System & Prescriptions 02:25:24 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 01, 2024

    Dr. Gabrielle Lyon: How to Exercise & Eat for Optimal Health & Longevity

    Dr. Gabrielle Lyon: How to Exercise & Eat for Optimal Health & Longevity
    In this episode, my guest is Dr. Gabrielle Lyon, D.O., a board-certified physician who did her clinical and research training at Washington University in geriatrics and nutrition. She is also an expert in how diet and exercise impact muscle and whole-body health and longevity. Dr. Lyon is a bestselling author and public educator. We discuss how healthy skeletal muscle promotes longevity, brain health, disease prevention, ideal body composition, and the health of other organs and bodily systems. She makes specific nutritional recommendations for optimal health: what to eat, how much to eat, the timing of meals, the essential need for adequate quality protein (including animal and plant-based options), supplementation, and how our dietary requirements change with age. She explains why specific types of resistance training are essential to build and maintain muscle and overall metabolic health. She also describes how to include resistance training as part of your exercise regimen — regardless of age or sex.  She also provides specific mindset tools to encourage sustained adherence to healthy eating and exercise practices. Women and men of all ages will benefit from Dr. Lyon’s practical, evidence-based protocols to improve muscle and whole-body appearance, function, and health. Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com. Andrew's New Book Protocols: An Operating Manual for the Human Body: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman  Levels: https://levels.link/huberman  Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://insidetracker.com/huberman  Timestamps 00:00:00 Protocols Book; Dr. Gabrielle Lyon 00:03:23 Sponsors: Maui Nui, Levels & Helix Sleep 00:07:40 Skeletal Muscle & Longevity 00:11:25 “Under-muscled”, Leucine & Muscle Health 00:15:55 Muscle Health 00:19:45 Tool: Carbohydrate Consumption & Activity, Glycogen 00:25:14 Tools: Nutrition for Healthy Skeletal Muscle, First Meal 00:31:57 Sponsor: AG1 00:33:46 Quality Protein, Animal & Plant-Based Proteins 00:37:36 Dietary Protein Recommendations, Meal Threshold 00:41:19 Muscle Health & Aging 00:46:02 Supplements & Creatine; Dietary Protein 00:50:07 Tool: Dietary Protein Recommendation; Gout & Cancer Risk 00:52:43 Effects of Dietary Protein & Exercise on Body Composition 01:03:06 Thermic Effects, Protein  01:05:02 Sponsor: InsideTracker 01:06:14 Protein & Satiety, Insulin & Glucose 01:12:04 Tool: Older Adults, Resistance Training & Dietary Protein 01:17:48 Dietary Protein, mTOR & Cancer Risk 01:21:36 Muscle Span & Aging, Sedentary Behaviors 01:24:00 Mixed Meals, Protein Quality, Fiber 01:29:21 Inactivity & Insulin Resistance, Inflammation 01:38:43 Exercise & Myokines, Brain Health & BDNF 01:44:11 Tool: Resistance Training Protocols, Hypertrophy, “High Ground” 01:52:51 High Ground Exercises; Tendon Strength; Training Duration, Blue Zones 01:58:19 Movement, Exercise & Older Adults 02:04:25 Tool: Protein Timing & Resistance Training; VO2 Max, Aging, Blood Work 02:11:13 Supplements: Creatine, Urolithin A, Whey Protein, Fish Oil, Collagen 02:20:18 Fasting, Older Adults; Tool: Meal Timing 02:25:18 Animal Proteins & Dairy; Organ Meats, Vegan; Magnesium, Zinc 02:30:59 Medications & Muscle Health 02:32:49 Obesity & GLP-1 Analogs, Ozempic, Mounjaro, Skeletal Muscle 02:40:48 Benefits of Skeletal Muscle & Aging 02:42:16 Tools: Nutrition & Resistance Training for Muscle Health 02:45:44 Mindset Tools: Standards vs. Goals; Vulnerability Points 02:52:00 Mindset Tools: Neutrality; Health & Worth 03:01:14 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter, Protocols Book Disclaimer
    Huberman Lab
    enJune 24, 2024

    Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

    Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It
    I'm honored to share Episode 2 of the first season of Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 features 10 episodes, airing every Wednesday for 10 weeks. Dr. Galpin will cover everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 2 of Perform with Dr. Andy Galpin here, please be sure to subscribe and follow Perform with Dr. Andy Galpin on your preferred platform. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:06 Skeletal Muscle 00:04:06 Sponsors: Absolute Rest & Momentous 00:07:20 Quantity & Quality; Organ System; Health & Performance 00:12:58 Plasticity, “Look Good, Feel Good, Play Good”; Muscle Types 00:15:46 What is Muscle?, Muscle Fibers, Tendon 00:21:37 Muscle Fiber Number, Hyperplasia, Anabolic Steroids, Age 00:24:03 Myonuclei & Adaptability 00:26:27 Muscle Fiber Types, Variable Muscle Functions 00:32:24 Fiber Type & Lifestyle Factors 00:34:54 Sponsors: David Protein & AG1 00:37:37 Age & Muscle Loss, Slow vs. Fast-Twitch Fibers; Motor Units 00:46:36 Muscle Size vs. Muscle Strength, Quantity vs. Quality 00:50:56 Investigate: Muscle Quantity, Fat-Free Mass Index (FFMI) 00:56:21 FFMI, Elite Athletes, Muscle Mass 01:00:59 Muscle Asymmetry; Too Much Muscle Possible? 01:03:49 Interpret: Muscle Mass, FFMI Calculations & Percentiles 01:09:28 Tool: Intervene - Increase Muscle Mass, 72-Hour Rule 01:15:27 Sponsors: Maui Nui & Renaissance Periodization 01:17:51 Investigate: Muscle Quality & 4 Movement Principles 01:23:34 Muscle Quality & 3 Performance Principles  01:26:42 Interpret: Muscle Speed, Age 01:32:45 Muscle Power, Vertical Jump, Broad Jump 01:36:17 Muscle Strength, Powerlifting Elite, Bench Press, Leg Press, Grip Strength 01:44:05 Increasing Strength, Improve Health & Longevity 01:46:44 Tool: Intervene - Improve Muscle Quality, 4 Training Principles, 3-to-5 Rule 01:53:56 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media 01:56:10 Conclusion from Dr. Andrew Huberman Disclaimer
    Huberman Lab
    enJune 19, 2024

    Dr. Zachary Knight: The Science of Hunger & Medications to Combat Obesity

    Dr. Zachary Knight: The Science of Hunger & Medications to Combat Obesity
    In this episode, my guest is Dr. Zachary Knight, Ph.D., a professor of physiology at the University of California, San Francisco (UCSF), and Howard Hughes Medical Institute (HHMI) investigator. We discuss how the brain controls our sense of hunger, satiety, and thirst. He explains how dopamine levels impact our cravings and eating behavior (amount, food choices, etc) and how we develop and can change our food preferences and adjust how much we need to eat to feel satisfied. We discuss factors that have led to the recent rise in obesity, such as interactions between our genes and the environment and the role of processed foods and food combinations. We also discuss the new class of medications developed for the treatment of obesity and diabetes, including the GLP-1 agonists semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro). We discuss how these medications work to promote weight loss, the source of their side effects, and the newer compounds soon to overcome some of those side effects, such as muscle loss. Dr. Knight provides an exceptionally clear explanation for our sense of hunger, thirst, and food cravings that translates to practical knowledge to help listeners better understand their relationship to food, food choices, and meal size to improve their diet and overall health. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman  BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Waking Up: https://wakingup.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Zachary Knight 00:02:38 Sponsors: BetterHelp, Helix Sleep & Waking Up 00:07:07 Hunger & Timescales 00:11:28 Body Fat, Leptin, Hunger 00:17:51 Leptin Resistance & Obesity 00:20:52 Hunger, Food Foraging & Feeding Behaviors, AgRP Neurons 00:30:26 Sponsor: AG1 00:32:15 Body Weight & Obesity, Genes & POMC Neurons 00:39:54 Obesity, Genetics & Environmental Factors 00:46:05 Whole Foods, Ultra-Processed Foods & Palatability 00:49:32 Increasing Whole Food Consumption, Sensory Specific Satiety & Learning 00:58:55 Calories vs. Macronutrients, Protein & Salt 01:02:23 Sponsor: LMNT 01:03:58 Challenges of Weight Loss: Hunger & Energy Expenditure 01:09:50 GLP-1 Drug Development, Semaglutide, Ozempic, Wegovy 01:19:03 GLP-1 Drugs: Muscle Loss, Appetite Reduction, Nausea 01:23:24 Pharmacologic & Physiologic Effects; GLP-1 Drugs, Additional Positive Effects 01:30:14 GLP-1-Plus Development, Tirzepatide, Mounjaro, AMG 133 01:34:49 Alpha-MSH & Pharmacology 01:40:41 Dopamine, Eating & Context 01:46:01 Dopamine & Learning, Water Content & Food 01:53:23 Salt, Water & Thirst 02:03:27 Hunger vs. Thirst 02:05:46 Dieting, Nutrition & Mindset 02:09:39 Tools: Improving Diet & Limiting Food Intake 02:14:15 Anti-Obesity Drug Development 02:17:03 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJune 17, 2024

    Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

    Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
    I'm honored to share the first episode of the new podcast, Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I’m delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 features 10 episodes, airing every Wednesday for 10 weeks. Dr. Galpin will cover everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 1 of Perform with Dr. Andy Galpin here, please be sure to subscribe and follow Perform with Dr. Andy Galpin on your preferred platform. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:07 Heart 00:03:55 Sponsors: Vitality Blueprint & Rhone 00:07:27 Muscle Types 00:09:54 VO2 max, Health & Mortality 00:15:49 Overall Health, Cardiorespiratory Fitness & All-Cause Mortality 00:25:23 Sponsor: AG1 00:26:54 Disease, Health & Mortality 00:30:02 Cardiac Muscle & Heart 00:38:29 Cardiac Muscle vs. Skeletal Muscle, Cardiac Advantages 00:43:53 Pacemakers & Heart Rate, Vagus Nerve 00:50:35 Why Doesn’t the Heart Get Sore? 00:54:32 Heart & Exercise, Stroke Volume, Ejection Fraction, Cardiac Output 00:59:21 Heart Rate Variability 01:02:41 Sponsors: Momentous & LMNT 01:06:54 Why Do You Breathe?: Oxygen, Carbon Dioxide & Respiratory Rate 01:13:37 Respiratory Rate & Stress 01:15:08 Tool: The “Three I’s”, Investigate: Heart Rate, Respiratory Rate, VO2 Max 01:19:53 Tool: Interpretation, Resting Heart Rate & Ranges 01:23:16 Tool: Interpretation: VO2 Max & Ranges 01:30:45 Athletes & Highest VO2 Max Scores 01:35:53 Elite Athletes & Context for VO2 Max Scores 01:41:42 Tool: Intervention, VO2 Max, Varying Exercise Intensities, SAID Principle 01:48:20 Tool: Varying Exercise Intensity; Intervals & Continuous Training; Frequency 01:58:18 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media 01:59:55 Conclusion from Dr. Andrew Huberman Disclaimer
    Huberman Lab
    enJune 12, 2024

    Dr. Jonathan Haidt: How Smartphones & Social Media Impact Mental Health & the Realistic Solutions

    Dr. Jonathan Haidt: How Smartphones & Social Media Impact Mental Health & the Realistic Solutions
    In this episode, my guest is Dr. Jonathan Haidt, Ph.D., professor of social psychology at New York University and bestselling author on how technology and culture impact the psychology and health of kids, teens, and adults. We discuss the dramatic rise of suicide, depression, and anxiety as a result of replacing a play-based childhood with smartphones, social media, and video games. He explains how a screen-filled childhood leads to challenges in psychological development that negatively impact learning, resilience, identity, cooperation, and conflict resolution — all of which are crucial skills for future adult relationships and career success. We also discuss how phones and social media impact boys and girls differently and the underlying neurobiological mechanisms of how smartphones alter basic brain plasticity and function.  Dr. Haidt explains his four recommendations for healthier smartphone use in kids, and we discuss how to restore childhood independence and play in the current generation.  This is an important topic for everyone, young or old, parents and teachers, students and families, to be aware of in order to understand the potential mental health toll of smartphone use and to apply tools to foster skill-building and reestablish healthy norms for our kids. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman  Helix Sleep: https://helixsleep.com/huberman AeroPress: https://aeropress.com/huberman Joovv: https://joovv.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Jonathan Haidt 00:02:01 Sponsors: Helix Sleep, AeroPress & Joovv 00:06:23 Great Rewiring of Childhood: Technology, Smartphones & Social Media 00:12:48 Mental Health Trends: Boys, Girls & Smartphones 00:16:26 Smartphone Usage, Play-Based to Phone-Based Childhood 00:20:40 The Tragedy of Losing Play-Based Childhood 00:28:13 Sponsor: AG1 00:30:02 Girls vs. Boys, Interests & Trapping Kids 00:37:31 “Effectance,” Systems & Relationships, Animals 00:41:47 Boys Sexual Development, Dopamine Reinforcement & Pornography 00:49:19 Boys, Courtship, Chivalry & Technology; Gen Z Development 00:55:24 Play & Low-Stakes Mistakes, Video Games & Social Media, Conflict Resolution 00:59:48 Sponsor: LMNT 01:01:23 Social Media, Trolls, Performance 01:06:47 Dynamic Subordination, Hierarchy, Boys 01:10:15 Girls & Perfectionism, Social Media & Performance 01:14:00 Phone-Based Childhood & Brain Development, Critical Periods 01:21:15 Puberty & Sensitive Periods, Culture & Identity 01:23:55 Brain Development & Puberty; Identity; Social Media, Learning & Reward 01:33:37 Tool: 4 Recommendations for Smartphone Use in Kids 01:41:48 Changing Childhood Norms, Policies & Legislature 01:49:13 Summer Camp, Team Sports, Religion, Music 01:54:36 Boredom, Addiction & Smartphones; Tool: “Awe Walks” 02:03:14 Casino Analogy & Ceding Childhood; Social Media Content 02:09:33 Adult Behavior; Tool: Meals & Phones 02:11:45 Regaining Childhood Independence; Tool: Family Groups & Phones 02:16:09 Screens & Future Optimism, Collective Action, KOSA Bill 02:24:52 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJune 10, 2024

    LIVE EVENT Q&A: Dr. Andrew Huberman at the Brisbane Convention & Exhibition Centre

    LIVE EVENT Q&A: Dr. Andrew Huberman at the Brisbane Convention & Exhibition Centre
    Recently I had the pleasure of hosting a live event in Brisbane, Australia. This event was part of a lecture series called The Brain Body Contract. My favorite part of the evening was the question and answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event at the Brisbane Convention & Exhibition Centre. Sign up to get notified about future events: https://www.hubermanlab.com/events Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Resources Mentioned Huberman Lab Non-Sleep Deep Rest Protocols Huberman Lab Guest Series with Dr. Matt Walker Huberman Lab Guest Series with Dr. Paul Conti Huberman Lab Guest Series with Dr. Andy Galpin Dr. Becky Kennedy: Protocols for Excellent Parenting & Improving Relationships of All Kinds Perform with Dr. Andy Galpin Timestamps 00:00 Introduction 00:31 Sponsors: AG1 & Eight Sleep 03:48 Nicotine Discussion 07:42 ADHD Management: Tools & Medications 12:43 Sleep Deprivation & Recovery 18:54 Understanding & Addressing Burnout 22:12 Daily Nutrition & Eating Habits 24:40 Understanding Food & Neural Pathways 26:21 The Benefits of Elimination Diets 27:21 Intermittent Fasting & Personal Diet Choices 28:23 Top Health & Fitness Recommendations 30:50 The Value of Non-Sleep Deep Rest (NSDR) 33:08 Testosterone Replacement Therapy Insights 38:02 Breathing Techniques for Stress & Focus 41:46 Morning Sunlight & Circadian Rhythms 43:18 Parenting Tips for a Healthy Start 49:03 Final Thoughts & Gratitude Disclaimer
    Huberman Lab
    enJune 07, 2024

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