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    The Science Of Your Gut Microbiome: How Healing Your Gut Can Improve Your Physical and Mental Health with Dr. Steven Gundry

    enJanuary 10, 2024

    Podcast Summary

    • Understanding the Power of the Gut MicrobiomePrioritizing gut health through dietary changes can effectively address modern diseases, as explained by Dr. Steven Gundry in his book "Gut Check.

      The gut microbiome plays a crucial role in our overall health and well-being. Despite its importance, conventional medicine has not fully integrated this knowledge into teaching and practice. Dr. Steven Gundry, a renowned cardiothoracic surgeon and pioneer in nutrition, emphasizes the significance of the gut microbiome in his latest book, "Gut Check." He explains that colorful plant compounds called polyphenols and the production of postbiotics in the gut have a profound impact on our health. Dr. Gundry also explores the connection between the gut microbiome and mood disorders, cancer treatment, and leaky gut. This conversation highlights the need to prioritize gut health and utilize dietary changes to address modern diseases effectively.

    • The Importance of a Healthy Gut Microbiome and Its Impact on Health and Well-being.Taking care of our gut microbiome through a five-step program can lead to significant improvements in various health conditions, and it is crucial for traditional healthcare practitioners to be aware of its significance.

      The health of our gut microbiome is crucial for overall well-being. Functional medicine practitioners have long recognized the importance of a healthy gut in addressing various health issues. By following a five-step program that includes removing harmful substances, replacing missing enzymes and bacteria, repairing the gut lining, and restoring balance, patients have experienced significant improvements in conditions like arthritis, depression, autoimmune diseases, and migraines. Despite the growing attention and scientific understanding of the microbiome, many traditional healthcare practitioners are not aware of its significance. This lack of awareness means that individuals suffering from a range of conditions, from heart disease to allergies, may not receive the comprehensive care they need. Understanding and nurturing our gut microbiome is key to promoting overall health and longevity.

    • The Importance of Microbiome Diversity and Nourishing Your GutMaintaining a diverse microbiome through a diet rich in prebiotic fiber and polyphenols is essential for overall health, protecting against chronic diseases, and supporting the immune system, hormones, and mental health.

      A diverse and healthy microbiome is crucial for overall health. This can be seen in populations like the Hanza, who have a wide range of bacteria species in their gut. These diverse microbiomes contribute to their good health and protection against chronic Western diseases. In contrast, Western diets and the lack of prebiotic fiber have led to a decline in microbial diversity in our guts. This has adverse effects on our immune system, hormones, mental health, and increases the risk of various diseases. Additionally, the discovery that polyphenols, found in colorful fruits and vegetables, play a crucial role in nourishing the microbiome is significant. By understanding the importance of microbiome diversity and providing the necessary nutrients, we can effectively support our own health and well-being.

    • The Importance of Gut Microbiome Diversity and Polyphenols in Maintaining Gut HealthA diverse and nutrient-rich diet, along with strategies to support mitochondrial function, can significantly improve gut health and overall well-being.

      Our gut health is intricately tied to the complexity and diversity of our gut microbiome. Just like a monocrop cornfield is vulnerable to disease, a lack of microbial diversity in our gut can lead to various health issues. This decline in microbial diversity is often a result of our modern diet, which is low in fiber, prebiotics, and polyphenols. Polyphenols, found in foods like pomegranates, cranberries, and green tea, are particularly important for promoting the growth of beneficial bacteria like Akkermansia. Furthermore, maintaining a healthy gut wall is essential for overall health, and a concept called mitochondrial uncoupling plays a role in this process. Mitochondrial uncoupling allows mitochondria, the energy powerhouses of our cells, to efficiently produce energy without causing excessive damage. Prioritizing a diverse and nutrient-rich diet, along with strategies to support mitochondrial function, can have a profound impact on gut health.

    • The Benefits of Uncoupling Mitochondria for Energy Production and HealthUncoupling mitochondria improves energy production by releasing wasted calories. It also signals the need for more mitochondria, leading to increased efficiency and overall health. Polyphenols in plants aid in this process.

      Uncoupling mitochondria can have beneficial effects on energy production and overall health. Uncoupling allows for the release of protons that don't participate in making energy, resulting in wasted calories. However, this uncoupling also generates heat, which is important for warm-blooded animals like us. Uncoupling signals the need for more mitochondria, leading to mitochondrial biogenesis. This increased mitochondrial capacity allows for more efficient energy production and distribution, similar to adding more dogs to a sled. Interestingly, the people who live the longest have the most uncoupled mitochondria. Polyphenols, found in colorful plants, play a role in uncoupling mitochondria, providing protection from harmful stressors and promoting overall health.

    • The Symbiotic Relationship Between Humans and PlantsHumans and plants have a mutually beneficial relationship, where plants use us to distribute their seeds and we benefit from the positive impact of polyphenols on our biology. The gut microbiome also plays a crucial role in processing these compounds.

      Humans have a symbiotic relationship with plants, using their molecules to optimize our health. This concept, called symbiotic phyto adaptation, highlights how we have co-evolved with plants over time. While plants may not necessarily care about what happens to us, they benefit from using us to distribute their seeds. Polyphenols, which act as the plants' defense mechanisms, play a crucial role in this relationship. It's important to understand that polyphenols are not antioxidants, but rather signaling compounds that have a positive impact on our biology. The gut microbiome also plays a key role in processing these polyphenols. This new understanding brings to light the intricate communication system between the gut microbiome, our DNA, and our mitochondria, which are believed to be ancient engulfed bacteria.

    • The Surprising Connection Between Farts, Microbiome, and MitochondriaFarts might actually be a form of communication between our microbiome and mitochondria, highlighting the importance of gaso transmitters in maintaining a healthy microbiome and overall well-being.

      Our mitochondria, which are essential for energy production in our cells, are inherited solely from our mother. This means that our initial microbiome, the community of bacteria in our body, also comes from our mother. There is a theory that suggests the maternal microbiome communicates with the maternal mitochondria through a language that includes gaso transmitters. Surprisingly, the farts we produce are actually a means of communication between the microbiome and the mitochondria. For example, hydrogen gas produced through the fermentation of prebiotic fiber might play a crucial role in mitochondrial function. This was demonstrated when patients with early-onset Parkinson's disease, who had low hydrogen gas production, showed improvements when given hydrogen water. Understanding the importance of gaso transmitters in our body can help us take better care of our microbiome and overall health.

    • The Role of Gut Buddies and Postbiotics in Our HealthTaking care of our gut buddies and promoting gut diversity through fermented foods and prebiotic fiber can have a profound impact on our overall health by regulating our biology and reducing inflammation.

      Our gut microbiome plays a crucial role in our overall health. The presence of good bacteria, known as gut buddies, is essential for maintaining a healthy microbiome. These gut buddies produce postbiotics, which are molecules that regulate our biology and have profound impacts on our health. One important postbiotic is Urolithin A, which is produced by certain bacteria from consuming foods like pomegranates, walnuts, and raspberries. However, only a small percentage of people can produce Urolithin A, while supercentenarians have a higher percentage of these bacteria. This demonstrates the importance of taking care of our gut buddies and inviting more good bacteria into our microbiome. Additionally, consuming fermented foods along with prebiotic fiber can promote gut diversity and reduce inflammation, highlighting the significance of communication within the gut microbiome.

    • The Powerful Role of Gut Bacteria and Communication in Overall HealthOur gut bacteria communicate with each other through postbiotics, influencing their actions and utilization of prebiotics. Nurturing our gut health is vital for optimal physical performance and overall well-being.

      The bacteria in our gut play a crucial role in our overall health. It's not just about having active yogurt cultures or taking probiotics, but rather the dead bacteria cell wall and postbiotics created during fermentation that have significant effects. These compounds carry messages that are read by other bacteria, influencing their actions. Additionally, we now know that bacteria leave messages for each other, similar to how dogs leave urine messages for other dogs. This communication is vital in telling other bacteria how to utilize prebiotic fiber. Furthermore, the gut microbiome has a profound impact on our body. It produces molecules that affect muscle endurance, strength, fitness levels, inflammation, metabolism, and immune function. Understanding and nurturing our gut health is crucial for overall well-being.

    • The Microbiome: A Key Player in Health and Well-beingOur microbiome not only impacts our mood and mental well-being but also influences cancer risk and response to drugs. Protecting and maintaining a healthy microbiome is vital for our overall health.

      The microbiome plays a crucial role in our overall health, including mood, cancer risk, and response to certain drugs. The presence of specific bacteria in the gut can influence our mood and mental well-being, with depressed individuals having a depressive microbiome. Furthermore, the use of glyphosate as a weed killer, even in small amounts, can have detrimental effects on the microbiome, disrupting the production of neurotransmitters that regulate mood. Additionally, the microbiome is not only linked to mental health but also to cancer risk and treatment response. Studies have shown that an altered microbiome can increase the risk of cancer and affect how individuals respond to immunotherapy drugs. Therefore, taking care of our microbiome is essential for maintaining overall health.

    • Unraveling the Role of the Microbiome in Cancer and Toxin MetabolismThe microbiome has potential implications in cancer treatment and detoxification, emphasizing the importance of personalized medicine and further research into the role of microbes in our well-being.

      The microbiome plays a crucial role in predicting and potentially treating various types of cancer. While the exact relationship between the microbiome and cancer is still not fully understood, there is evidence to suggest that specific types of microbes may either cause or facilitate the development of cancer. Additionally, certain patients may respond better to chemotherapy if targeted antibiotics are used to alter their microbiome. This highlights the potential of personalized medicine and the need to further investigate the role of microbes in cancer. Furthermore, the microbiome has been found to have the ability to metabolize environmental toxins, such as xenobiotics found in plastics and petrochemical products. This suggests that probiotics or specific dietary changes may help offset the harmful effects of such toxins. Overall, the microbiome is a fascinating and powerful component of our health that is still being explored and understood.

    • The Gut Microbiome: A Key Factor in Mental Well-beingTaking care of our gut by eliminating harmful foods and supplementing with beneficial bacteria can have remarkable improvements on mental health and overall well-being.

      The health of our gut microbiome has a profound impact on our mental health. Research shows that certain bacteria in the gut can affect brain function and emotions, including conditions like OCD, anxiety, and depression. By treating the gut and restoring a healthy microbiome, remarkable improvements in mental health can be seen. This can involve eliminating foods contaminated with glyphosate, such as oats, which can harm the gut bacteria. Additionally, supplementing with beneficial bacteria, like El Riter, can have positive effects on oxytocin production and even improve hair and skin health. Taking care of our gut is a key factor in maintaining overall mental well-being.

    • The importance of gut health and its impact on chronic diseasesBy eliminating gluten and other harmful components from our diet and avoiding foods that contain lectins, we can improve our gut health and alleviate symptoms of autoimmune conditions, diabetes, and coronary artery disease.

      Taking care of our gut health is crucial for reversing disease and improving our overall well-being. Dr. Gundry emphasizes the importance of addressing autoimmune conditions, diabetes, and coronary artery disease by eliminating gluten and other harmful components found in wheat and rye. He explains that leaky gut is a prevalent issue for many individuals and can be managed by removing gluten from the diet. Additionally, he warns against consuming foods that contain lectins, such as almonds, as they can contribute to inflammation and trigger certain health conditions. By adopting a gut-friendly diet and avoiding harmful substances, we can repair our gut and alleviate symptoms of chronic diseases.

    • Healing the Gut for Better HealthRepairing and nurturing our gut microbiome is essential for improving autoimmune conditions. Functional medicine offers effective methods to heal the gut and restore its optimal function, leading to a healthier future for 94% of people.

      Our gut health plays a crucial role in our overall well-being, including autoimmune conditions. The presence of certain antibodies in our system, developed in response to specific plant components like aquaporins found in spinach, can trigger autoimmune attacks. However, by repairing and nurturing our gut microbiome, we can significantly improve our tolerance and alleviate symptoms. Functional medicine offers effective methods to heal the gut and restore its optimal function. It's not just about avoiding trigger foods; it's about addressing the underlying reasons for our sensitivities. The exciting part is that a staggering 94% of people can resolve their autoimmune issues through gut restoration. By continually seeking knowledge and following the evolving science, we can pave the way for a healthier future.

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    Resources: 

    Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, Schleimer RP, Nadeau KC. Prevalence and Severity of Food Allergies Among US Adults. JAMA Netw Open. 2019 Jan 4;2(1):e185630. doi: 10.1001/jamanetworkopen.2018.5630. PMID: 30646188; PMCID: PMC6324316.

     Warren CM, Jiang J, Gupta RS. Epidemiology and Burden of Food Allergy. Curr Allergy Asthma Rep. 2020 Feb 14;20(2):6. doi: 10.1007/s11882-020-0898-7. PMID: 32067114; PMCID: PMC7883751.

    Niewiem M, Grzybowska-Chlebowczyk U. Intestinal Barrier Permeability in Allergic Diseases. Nutrients. 2022;14(9):1893. Published 2022 Apr 30. doi:10.3390/nu14091893

     

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    Moon Mining and the Microbiome with Naveen Jain, Founder of Viome

    In this episode, we sit down with Naveen Jain, Founder of Viome.

    Naveen is an entrepreneur and philanthropist who is driven to solve the world's biggest challenges through innovation. His company Viome is on a mission to help people understand what they uniquely need to be healthy through at-home health kits and precise food and supplement recommendations.

    In this episode, we talk to Naveen about everything from the science and consumer safety behind Viome to their newest test kits that take your biological age and mitochondrial health into account. We also nerd out about Naveen's passion project: The Moon!


    USE DISCOUNT CODE "B&B" at checkout for $10 OFF YOUR FIRST ORDER at https://www.viome.com.


    ABOUT BEAUTY & THE BIOHACKER:


    ABOUT RACHEL & KATIE:


    DISCLAIMER: Information in this podcast and interview is not to be taken as medical advice, and always consult with your Physician before making any lifestyle changes. The material shared by guests in this podcast is not the opinion of Rachel Varga or Katie Moore, and disclaims any responsibility of inaccurate credentials of guests or information used that may cause harm. Always consult with your licensed Physician before any lifestyle modifications.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    How To Address Gut Issues And Get Back To Optimal Health

    How To Address Gut Issues And Get Back To Optimal Health

    This episode is brought to you by AG1, AirDoctor, HigherDOSE, and Super Simple Protein


    So many people are plagued every day with uncomfortable symptoms like bloating, cramps, diarrhea, constipation, and pain that often reduce quality of life or derail daily activities. Thankfully, emerging research has helped identify the real underlying issues of digestive conditions, which means we are developing an understanding of how to actually treat—and fix—gut dysfunction.


    In today’s episode, I talk with Dhru Purohit and Dr. Elizabeth Boham about the importance of a healthy gut and how to treat common symptoms like bloating, malnutrition, dysbiosis, and more.


    Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.


    Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing.


    This episode is brought to you by AG1, AirDoctor, HigherDOSE, and Super Simple Protein.


    Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase.


    I’ve teamed up with the makers of AirDoctor to give my listeners the best deal yet on this amazing filtration system. Right now, if you go to drhyman.com/filter you can get the AirDoctor filter for $329.


    Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout or just go to higherdose.com/hyman to save 15% site-wide.


    Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10.


    Full-length episodes (and corresponding links) of these interviews can be found here:

    3 Things That Destroy Your Gut Health

    Underweight, Overtired, and Malnourished: How To Get Your Health Back On Track

    Why Gut Issues Are On The Rise And How To Fix It

    Bloating: Getting Rid Of Your Food Baby With Functional Medicine




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