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    #294 ‒ Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu

    A higher VO2 max indicates greater energy production capacity and better athletic performance. In the medical field, a lower VO2 max can indicate higher energy demand during stress or illness.

    enMarch 18, 2024

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    Olav Aleksander Bu is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines. In this episode, Olav delves deep into the intricacies of VO2 max and its profound impact on performance. They explore the relationship between VO2 max and ATP production, energy efficiency, and power, as well as the impact of low-intensity training on VO2 max. The conversation extends to Olav’s experiences pushing the boundaries with high-performance athletes and the data driven interventions he uses to improve performance. They also dissect the role of lactate threshold, discuss other important metrics to track, and explore the exciting possibility of utilizing a portable VO2 testing device as a practical alternative to traditional lab-based assessments.

    We discuss:

    • Olav’s background, expertise in exercise physiology, coaching experience, and interest in the extremes of human capability [4:15];
    • The processes of energy conversion within the human body and its implications for performance [9:30];
    • Improving movement efficiency, and the importance of mindfulness in training to optimize performance [20:00];
    • The relationship between VO2 max, power output, and endurance performance in different sporting contexts [34:45];
    • How VO2 max is measured in the lab, and why it’s a crucial predictor of both lifespan and quality of life [44:45];
    • Absolute vs relative VO2 max, the significance of functional threshold power in cycling, and the importance of longer duration tests for accurate assessments [54:00];
    • Portable VO2 testing devices as a practical alternative to lab-based tests [1:05:15];
    • The complexities of measuring ventilation and its impact on performance metrics like VO2 max and heart rate [1:15:45];
    • Training interventions to increase VO2 max, and factors that impact performance outcomes [1:23:30];
    • The respiratory exchange ratio (RER) and endurance sports, and how factors such as diet composition and exercise intensity influence RER values and performance [1:32:45];
    • Science-guided training for versatile athletes: maximizing VO2 max, power, torque, and cadence in cycling, and the importance of incorporating diverse stimuli to enhance performance [1:41:00];
    • Physiological limitations on VO2 max [2:02:15];
    • The different energy systems used during work, and other things to monitor like VCO2 and heart rate [2:06:00];
    • Lactate threshold and other metrics to guide your training [2:10:30];
    • Analysis of a lactate power curve: exploring lactate dynamics in endurance training and performance [2:23:15]; and
    • More.

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    🔑 Key Takeaways

    • VO2 Max is a critical measure of cardiovascular fitness linked to ATP production efficiency, energy, and power. Absolute and relative values matter, weight influences results, and low-intensity training has benefits. Lactate testing and the VO2 Master provide insights into performance.
    • Understanding ATP production and utilization is crucial for optimizing performance in multi-disciplinary sports like triathlon
    • Understanding the complex metabolic process of producing ATP from food and oxygen is essential for optimizing performance and maintaining a healthy energy balance.
    • To achieve the best sports performance, athletes and trainers should consider velocity, power efficiency, and mechanical efficiency. Velocity determines winning, power efficiency optimizes energy usage, and mechanical efficiency minimizes energy loss.
    • Through consistent training and focusing on efficiency, athletes can improve their velocity by reducing drag and optimizing metabolic efficiency.
    • Wind tunnel testing is essential for identifying ideal positions, but maintaining that position off the bike requires mindful, low-intensity training. This approach allows athletes to focus on biofeedback and learn adjustments for significant improvements.
    • Highly efficient athletes, despite consuming more oxygen and calories, can perform better and live longer due to their high VO2 max.
    • Elite athletes prioritize sustainable energy expenditure over solely increasing VO2 max for optimal performance in specific sports
    • Max VO2 is essential, but power at VO2 max offers more insight into an athlete's performance capabilities. The duration and steady state of the test impact power at VO2 max. Advancements in technology make metabolic testing more accessible.
    • During metabolic testing, researchers measure oxygen consumption to determine energy expenditure and metabolic efficiency, providing valuable insights for athletes, healthcare professionals, and researchers.
    • A higher VO2 max indicates greater energy production capacity and better athletic performance. In the medical field, a lower VO2 max can indicate higher energy demand during stress or illness.
    • Weight loss can impact basal energy expenditure and metabolic pathways, affecting performance even at rest. Absolute power output is a better measure of cycling performance than watts per kilogram.
    • Functional threshold power is a reliable metric for predicting Tour de France performance, but its accuracy can be limited for shorter durations and by portable device measurements.
    • Home-testing devices like Jager Oxygen Pro, AEI Moxus, and VO2 Master provide accurate measurements of oxygen consumption and CO2 production during workouts using advanced technologies. These devices offer user-friendly designs and sync with various devices for easy access to key metrics.
    • Portable devices like the Oxygen Pro offer real-time insights into exercise metrics but may not match lab-based testing for accuracy due to differences in methods and external factors. Users must decide between absolute accuracy and real-world applicability based on their goals.
    • While oxygen intake impacts high-level athletes, it's insignificant for most individuals. Mixing chambers provide stable breathing patterns but measuring oxygen consumption can be volatile due to body's regulation and power relationship.
    • The human body functions like a dynamic, chaotic system, and small actions can significantly impact performance metrics. Calibration and adaptability are crucial for understanding and optimizing performance.
    • Consistently progressing hard efforts with recovery helps maintain power output and improve engine size. VO2 max measures aerobic power, not capacity, and individuals vary in their ability to sustain it. Rest and recovery are vital for harder efforts.
    • Short rest periods during high-intensity workouts can boost oxygen consumption and power output, but benefits diminish with longer rests. Temperature and RER also impact this effect.
    • VO2 is a more reliable indicator of performance, but during high-intensity endurance events, athletes may need to reduce oxygen consumption, making VO2 less accurate. WIC equation can be used to estimate energy expenditure by multiplying VO2 by 20, and lactate ratio can also be used as a surrogate but is less predictable.
    • During endurance events, oxygen intake is crucial as energy consumption exceeds digestive capacity. Athletes should prioritize training and understand body's response to stress to maximize performance.
    • Accumulating high-intensity work within a session can lead to increased engine size and overall fitness through the process of super compensation
    • Maximize VO2 max through both aerobic and anaerobic training, individualize programs with new technologies, and optimize energy expenditure by considering high torque, low velocity vs high velocity, low torque strategies.
    • Focus on increasing power output and total work during training sessions to stimulate cardiovascular and respiratory systems, leading to higher oxygen consumption
    • Shorter and longer intervals can enhance endurance by targeting various energy systems, providing a diverse range of stimuli for optimal training and performance
    • The body's oxygen consumption and carbohydrate utilization capacity exceeds previous beliefs, and the gastrointestinal tract is the limiting factor, not mitochondria. Efficiently using different energy systems requires accumulating enough work during a session.
    • During low-intensity exercise, RER doesn't significantly affect energy yield, but it's important for fueling strategy. Heart rate can indicate time near maximal effort during high-intensity intervals. Endurance training in zone two, where lactate production stays below 2mmol, is vital for long-term performance.
    • Endurance athletes should aim for sustainable training at a lactate level of around 2mmol for optimal performance and long-term health benefits.
    • Lactate threshold helps identify sustainable and unsustainable training paces by measuring lactate production. Repeated intervals and multiple measurements are necessary for accurate results.
    • Testing lactate threshold helps optimize training and performance by identifying distinct metabolic states, requiring specific protocols, and balancing fuel sources for optimal power output.
    • Experts discussed the importance of clear communication, ongoing research, and respect for terminologies in endurance sports performance. They emphasized the value of comprehensive resources for further learning.

    📝 Podcast Summary

    Understanding VO2 Max and its connection to fitness

    VO2 Max, a key indicator of cardiovascular fitness, is closely related to ATP production efficiency, energy, and power. Olav Alexander Bu, an endurance coach, exercise scientist, engineer, and physiologist, shared insights on this topic during his interview on The Drive Podcast. He emphasized the importance of understanding both absolute and relative VO2 Max values, the role of weight, and the benefits of low-intensity training. The discussion also delved into the role of lactate testing in performance and introduced the concept of the VO2 Master, a portable VO2 Max testing device. Listeners learned about the significance of VO2 Max in human performance and gained a deeper understanding of related concepts.

    Growing up on a farm and curiosity for tech fueled a passion for combining sports and technology

    The speaker's background growing up on a farm in Norway instilled in him a strong work ethic and appreciation for hardship, while also fueling his curiosity for technology and extreme sports. Later in life, he applied his engineering background and entrepreneurial spirit to combine technology and sports, focusing on studying and enhancing the performance of elite athletes through data and research. The triathlete, as a multi-disciplinary sport, requires athletes to be almost world-class in swimming, cycling, and running, resulting in unique physiological demands and training methods. The speaker emphasizes the importance of understanding the fundamentals of ATP production and utilization before delving into more complex topics related to extreme performance and peak athletic achievement.

    The process of converting food into ATP and fueling movements

    Our bodies convert chemical energy from food into electrical energy, which is then converted back into chemical energy (ATP) to fuel our movements. This process requires oxygen and can be thought of as having both metabolic pathways (converting food into ATP) and signaling pathways (regulating the process). The metabolic process is complex and still being researched, but it's important to remember that movement is the fundamental requirement for human life and that ATP, the energy currency for the body, is produced through the breakdown of various substrates (proteins, fats, carbohydrates) and the intake of oxygen. Understanding this energy production and consumption is crucial for optimizing performance and maintaining a healthy energy balance.

    Focus on velocity, power efficiency, and mechanical efficiency for optimal sports performance

    To optimize performance in training and understand the mechanisms behind it, it's crucial to focus on velocity as the primary metric, as it determines the winner in various sports. However, power and mechanical efficiency are also essential components to consider. Power efficiency refers to how effectively the body uses energy to produce ATP, while mechanical efficiency deals with minimizing energy loss and optimizing equipment usage. For instance, in cycling, maintaining a consistent power output of 200 watts during a time trial is important, but focusing solely on power can overlook the significance of mechanical efficiency and aerodynamics in achieving optimal velocity. By considering these three aspects – velocity, power efficiency, and mechanical efficiency – athletes and trainers can make informed decisions to improve performance and understand the underlying mechanisms.

    Focusing on drag and metabolism led to 1.5 mph increase in cycling velocity

    During a year-long training program, cyclists were able to increase their velocity from 20.5 mph to 22 mph by focusing on improving their coefficient of drag and metabolic efficiency. While it's unclear how much of the improvement came from each area without specific data, the use of a power meter allowed for consistent training at 200 watts, leading to better work economy and increased mindfulness of movement. The harder the effort, the more oxygen and blood are prioritized towards muscle movement and cooling, making it important for athletes to focus on efficient movement at lower power outputs. Additionally, specialists tend to prioritize feeling and efficiency over brute force, allowing them to make subtle adjustments and improvements based on measurable data like power output and velocity.

    Combining wind tunnel testing with mindful training for optimal aerodynamics

    Optimizing an athlete's position for improved aerodynamics goes beyond the wind tunnel. While wind tunnel testing is crucial for identifying the ideal position, it's essential to consider the athlete's ability to maintain that position off the bike. Without a clear outline or rehearsal, even minor adjustments can negate any gains made in the wind tunnel. This is particularly relevant when evaluating clothing on a live athlete. The cognitive effort required to adjust body position during low-intensity training can lead to significant improvements, such as reducing frontal surface area. This type of training is not "junk mileage" if done mindfully, as it allows athletes to focus on biofeedback and learn what adjustments will lead to the most significant improvements. The degree of freedom allowed in different sports, such as swimming, cycling, and running, affects the applicability of this training method. For instance, swimming requires exceptional spatial awareness and body control due to the vast number of degrees of freedom. In summary, optimizing an athlete's position for improved aerodynamics requires a holistic approach, combining wind tunnel testing with mindful, low-intensity training.

    The Importance of Efficiency in Sports Performance and Longevity

    There are highly efficient athletes, like swimmers Christian and Gustave, who have a larger engine size, consuming more oxygen and putting more calories to work than the world's best swimmers, despite being slower. This discovery highlights the importance of efficiency in sports performance and longevity. The discussion also emphasized the significance of VO2 max, the greatest predictor of lifespan, which integrates the work done over time. On the bike and run, just like in the pool, having a high VO2 max means you're able to consume more oxygen and put more energy into your movements, leading to better performance and potentially longer life.

    VO2 max might not be the best predictor for endurance performance in certain sports

    While VO2 max is an essential metric for understanding overall health and longevity, it may not be the best predictor of endurance performance in certain sports like cycling or running. This is because as an athlete, particularly an elite one, maximizing sustainable energy expenditure becomes crucial, and focusing solely on increasing VO2 max might mean less time spent specializing in the specific duration and intensity required for optimal performance in a given sport. It's essential to consider the context and limitations when evaluating the role of VO2 max in exceptional human performance.

    Understanding Power at VO2 Max

    While Max VO2 (the maximum amount of oxygen an athlete can consume per minute) is an important metric, focusing solely on it may not provide a complete picture. Power at VO2 max, or the amount of power an athlete can sustain at their maximum oxygen consumption, adds another layer of insight. However, it's important to note that the duration of the test and the specific steady state reached also play a role in determining power at VO2 max. Therefore, it's crucial to consider both metrics and the testing conditions to fully understand an athlete's performance capabilities. Additionally, advancements in technology are making metabolic testing more accessible, allowing individuals to measure and track their VO2 max and power at VO2 max more easily.

    Measuring Oxygen Consumption for Understanding Energy Metabolism

    During metabolic testing in a lab setting, researchers measure an individual's ventilation and oxygen consumption to determine their energy expenditure. This is important because energy, as measured in units like calories, is required for various biological processes, including the combustion of food for energy. The process of converting food into energy involves breaking down complex molecules, releasing hydrogen ions, and producing ATP. Oxygen is a crucial component of this process, and measuring oxygen consumption allows researchers to understand an individual's energy metabolism. This information can be valuable for athletes, healthcare professionals, and researchers studying various conditions. The testing is typically conducted using equipment that measures ventilation and oxygen concentration in exhaled air. By calculating the difference in oxygen concentration between inhaled and exhaled air and knowing the volume of air, researchers can determine the amount of oxygen consumed. This information, in turn, provides insights into an individual's energy expenditure and metabolic efficiency.

    Maximum oxygen consumption (VO2 max) and energy production capacity

    The maximum oxygen consumption (VO2 max) of an individual is a crucial metric in understanding their energy production capacity. By calculating VO2 max, we can determine how much energy is being released during physical activity. A higher VO2 max indicates a greater ability to produce energy, which can lead to better athletic performance and faster recovery. In the medical field, a lower VO2 max can indicate a higher energy demand during times of stress or illness, making it essential to have a good energy reserve. It's important to note that focusing on absolute VO2 max, rather than relative, provides a more accurate representation of an individual's energy production capacity. Additionally, reducing body weight to increase relative VO2 max may not always result in improved performance, as both absolute and relative values can decrease when body weight is reduced.

    Weight loss and cycling performance

    The relationship between weight loss and changes in VO2 max is more complex than just muscle mass loss. Reducing weight can impact basal energy expenditure and metabolic pathways, affecting performance even at rest. It's important to consider absolute values, such as power output, rather than just relative values, like watts per kilogram, when evaluating cycling performance, especially in less hilly races. Additionally, measuring resting metabolic rate can provide valuable insights into energy expenditure and performance. However, this method also has limitations and further research is needed to fully understand the complex relationship between weight loss, metabolism, and cycling performance.

    Measuring cycling performance in the Tour de France

    Functional threshold power, measured in watts per kilogram over a 60-minute period, can be a reliable metric for predicting cycling performance in the Tour de France. However, it's important to note that this metric has limitations, as shorter durations like 5 minutes can result in vastly different energy sources and thus, unreliable predictions if extrapolated to longer durations. Additionally, the accuracy of portable devices for measuring both oxygen consumption (VO2) and carbon dioxide production (VCO2) can be lacking, making them less effective for estimating total energy expenditure or measuring fat oxidation. Despite these limitations, functional threshold power is still a valuable tool for understanding an athlete's capabilities and potential performance.

    Measuring oxygen and CO2 levels during exercise with home-testing devices

    There are accurate enough home-testing devices available in the market for measuring oxygen and CO2 levels during exercise, such as the Jager Oxygen Pro and AEI Moxus. These devices use advanced technologies like zirconia cells for higher sensitivity and non-invasive designs for user convenience. The VO2 Master, a portable metabolic device, is an example that uses a hands-free mask, galvanic fuel cells, and differential pressure to measure oxygen consumption during workouts. The data collected can be synced with various devices like phones and Garmin computers for easy access and analysis of key metrics like breathing frequency, tidal volume, fraction of expired O2, VO2, power, velocity, and position. The convenience and accuracy of these devices enable athletes to monitor their progress regularly without feeling intrusive or invasive.

    Discrepancies between lab and portable fitness testing

    While portable devices like the Oxygen Pro offer real-time insights into heart rate, power, and estimated VO2 during exercise, they may not match the accuracy of lab-based metabolic testing equipment. This discrepancy can stem from differences in measurement methods and external factors like wind resistance. These devices provide approximate values in real-life conditions, making them valuable tools for athletes looking to monitor their performance in various situations. The difference in readings between lab and portable testing typically ranges from 50 milliliters, which is insignificant, to larger discrepancies depending on the specific conditions and athletes involved. Ultimately, the choice between absolute accuracy and real-world applicability depends on the user's goals and preferences.

    Impact of oxygen intake on athletes vs. regular individuals

    While a difference of 50 milliliters of oxygen intake may significantly impact high-level athletes, for most individuals, it is an insignificant factor. The use of mixing chamber systems in measuring oxygen consumption can provide more stable breathing patterns due to the added resistance. However, the measurement of ventilation and oxygen consumption can be volatile due to the body's regulatory mechanisms and the way power and oxygen consumption are related. These fluctuations can make it challenging to accurately measure and gauge the effectiveness of a system based on oxygen consumption alone. Instead, it is essential to consider the entire system's responsiveness and sensitivity to power and other factors.

    Understanding the complexities of the human body

    The human body is a complex system that goes beyond simple data readings. Even small actions like breathing or swallowing can impact performance metrics like power output and heart rate. These variations cannot be completely standardized or explained by a single equation. The body functions more like a dynamic, chaotic system, unlike the highly engineered components of a Formula One car. To better understand this complexity, try experimenting with your breathing and heart rate while maintaining a constant power output on a bike ride. Observe how changes in ventilatory rate affect these metrics, demonstrating the intricacies of the human body. Elite athletes also experience these fluctuations, highlighting the importance of calibration and adaptability.

    Maximizing a VO2 max workout

    Maximizing a VO2 max workout involves consistency, progression, and understanding the difference between aerobic power and aerobic capacity. The workout should include a series of hard efforts followed by recovery, with the goal of maintaining a similar power output throughout. It's important to note that VO2 max is a measure of aerobic power, not capacity, and individuals can vary greatly in their ability to sustain that power level. Additionally, consistency in training over time is crucial for improvement. Progressively increasing power output during workouts can help maximize the stimulus to the body and improve engine size. Rest and recovery are also essential to allow for harder efforts on subsequent sets.

    During high-intensity workouts, short rest periods enhance oxygen consumption and power output.

    During high-intensity interval training, the body's ability to consume oxygen and produce energy is enhanced when the rest period between intervals is short. This effect, known as "priming," can lead to improved power output and increased oxygen consumption in the subsequent intervals. However, if the rest period is too long, the benefits begin to diminish. The body's temperature also plays a role in this effect, as a higher temperature improves the affinity of hemoglobin for oxygen. Additionally, the ratio of carbon dioxide production to oxygen consumption (RER) is heavily skewed towards oxygen consumption during high-intensity intervals, which may not meet the traditional criteria for V2 max. The RER is calculated instantaneously and is influenced by the amount of energy being used at that moment. For example, during low-intensity exercise, such as riding a bike at 100 watts, the RER would be much lower than during high-intensity exercise.

    VO2 vs Lactate for Performance Measurement

    While both VO2 (volume of oxygen consumption) and lactate can be used to gauge an athlete's performance, VO2 is a more reliable indicator due to its volumetric measurement. However, during high-intensity endurance events, such as Ironman races, athletes may need to reduce their oxygen consumption to sustain their energy demands, making VO2 a less accurate predictor of performance. The WIC equation, which relates energy consumed to oxygen consumed and CO2 produced, can be simplified by multiplying oxygen consumption by 20 to estimate energy expenditure. At a VO2 of 6 liters per minute, this equates to approximately 30 calories per minute of energy consumption. The ratio between glucose and lactate can also be used as a surrogate, but it's important to note that lactate is influenced by many factors and can be less predictable than VO2.

    Understanding energy consumption during endurance events

    During endurance events, the body's energy consumption can exceed the human digestive system's capacity, making oxygen intake the key metric. The energetic demand becomes so high that prioritizing training becomes necessary. For instance, an Olympic distance triathlon requires an athlete to be at around 141.45 watts, while an Ironman distance requires around 270 watts. These huge energetic differences make it surprising that an athlete can excel in both. The use of science to understand the body's response to stress and maximize stimulus has been crucial in improving performance. Instead of focusing on sustaining the highest VO2 max, athletes should aim to accumulate the maximum amount of work at a certain output to grow their engine and increase their view to max.

    Stimulate the body to become faster by accumulating high-intensity work

    During exercise, the goal is to stimulate the body to become faster by accumulating high-intensity work, even if the maximum output decreases. This process, known as super compensation, can be achieved by repeating efforts within a session, leading to an increase in engine size and overall fitness. The key is to find the right balance between intensity and duration, ensuring the body is challenged but not overly stressed. Long sessions with extended recovery periods were once common, but modern training methods focus on shorter, high-intensity workouts. For example, accumulating 30 minutes of work at 300 watts, close to exhaustion, in a session lasting 75 to 90 minutes, can lead to significant improvements in fitness and speed.

    Understanding Energy Systems and Training Strategies for Athletic Performance

    Optimizing athletic performance involves understanding the role of various energy systems and training strategies. The discussion highlights the importance of both aerobic and anaerobic training, with a focus on maximizing VO2 max and efficient energy expenditure. New technologies, such as AI and data analysis, are being used to better understand and individualize training programs. The distinction between high torque, low velocity and high velocity, low torque strategies is significant, as it impacts the demand on the musculature and cardiovascular system. Ultimately, the goal is to improve conditioning and delay the age at which relative VO2 max falls below age and numbers.

    Increase power output and total work for better oxygen consumption during exercise

    To increase oxygen consumption during exercise, focus on increasing power output and total work during your training sessions, rather than just maintaining a high intensity for short periods. By increasing your power output and total work, you can stimulate your cardiovascular and respiratory systems more effectively, leading to a higher VO2 max. Additionally, maintaining a consistent cadence can help improve the balance between gross and net power, allowing you to recruit more muscle fibers and put out greater power without reaching a point of muscle recruitment saturation.

    Exploring different interval durations for endurance training

    Maximizing VO2 max through traditional three to eight minute intervals is not the only effective way to train and improve endurance. Shorter or longer intervals can also provide valuable stimuli for the body, leading to gains in energy systems that are flexible enough to oxidize both glucose and fatty acids through the mitochondria. The choice of interval duration depends on the specific training goals and the correlation between power and oxygen consumption, which starts to separate in lower durations. Ultimately, a diverse range of stimuli through different interval durations is important for optimal training and performance.

    Transportation of oxygen to cells is the rate-limiting step

    The rate limiting step in oxygen consumption or utilization is not at the mitochondria level, but rather at getting the oxygen and hemoglobin transported to the cells. The body's ability to use oxygen and carbohydrates for fuel is much higher than previously thought, and the gastrointestinal tract is the limiting factor, not the mitochondria. The body tries to use all energy systems instantly during high-intensity bursts, but the different energy systems get depleted over time. Therefore, it's essential to accumulate enough work during a session to maximize oxygen consumption and power output. The use of VCO2 is helpful in understanding the instantaneous picture of substrate use and the RIR value.

    Monitoring respiratory exchange ratio and heart rate during exercise

    During exercise, the relationship between oxygen consumption and carbon dioxide production, known as the respiratory exchange ratio (RER), does not have a significant impact on energy yield when it's below 0.8. However, it's essential to monitor RER for fueling strategy and understanding the utilization of fuels at different times. Additionally, heart rate can be used as an indicator of the time spent near maximal effort during high-intensity intervals. Furthermore, during endurance activities, training in zone two, where lactate production stays below 2 millimoles, is crucial for maximizing performance in the long term.

    The optimal lactate level for endurance athletes is around 2mmol

    The optimal lactate level for endurance athletes is around 2 millimoles, as this is the point where they can maintain a steady state of producing and clearing lactate without compromising their performance. This level can vary depending on individual capabilities and preferences, and the focus should be on sustainable training that brings joy and a sense of achievement. The long-term benefits of exercise, including improved wellness and longevity, should be prioritized over short-term pain and suffering. The joy of exercising is often undervalued, and a more sustainable approach to training can lead to better overall health and fitness.

    Understanding Lactate Threshold for Precise Training

    While the rate of perceived exertion is important for many people to enjoy their workouts, using metrics like lactate concentration can provide additional precision in training. Lactate is a marker of substrate utilization and can help athletes be more precise in their training by identifying their lactate threshold, which is the point at which lactate production becomes nonlinear and unsustainable. However, it's important to note that lactate concentration can vary based on factors like hydration and energy reserves, so it's essential to take multiple measurements and consider other metrics as well. The lactate threshold can be identified by performing repeated intervals at descending pace and measuring lactate concentration after each one to create a power curve. This can help athletes understand their sustainable and unsustainable lactate production and be mindful of exceeding that pace in races. It's also important to note that lactate concentration values are not fixed and can vary based on the protocol used, so it's crucial to consider the individual's specific circumstances when using this metric for training.

    Understanding an athlete's lactate threshold and metabolism

    Understanding an athlete's lactate threshold and its relationship to their metabolism is crucial for optimizing training and performance. The lactate threshold can be divided into different inflection points, each representing a distinct metabolic state. The first inflection point is similar to the fat max, while the second one is close to the maximum lactate steady state, also known as LT1 and LT2, respectively. Lactate threshold testing requires specific protocols, such as longer intervals and assessing lactate values every few minutes. Maximal lactate steady state is the highest lactate value an athlete can sustain without it accumulating, but it's not indefinitely sustainable. The maximal active steady state, which occurs at a lower R-R value for longer distances, is where an athlete can maintain their power output most sustainably. Highly powerful athletes may reach their maximal active steady state at around 80% of their VO2 Max, but their high carbohydrate intake can limit their fat oxidation capacity, making it essential to balance their fuel sources for optimal performance.

    Exploring Endurance Sports Performance and Optimization

    There is a vast amount of information and discussion surrounding the topic of endurance sports performance and optimization, and it's important for coaches and athletes to have a clear and effective communication to make the most out of their training. During a conversation between two experts, they covered various topics such as high-carb diets, muscle biopsies, anaerobic threshold, temperature probes, heart rate, heart rate variability, training, recovery, and PEDs usage. They emphasized the importance of having a shared understanding and respect for each other's terminologies and definitions, as long as it works for both parties. The conversation also highlighted the ongoing research and discovery in the field, and the importance of continuing to learn and adapt. The experts also encouraged an in-person follow-up discussion, and emphasized the value of comprehensive resources like podcasts, show notes, and newsletters for those interested in delving deeper into the topic.

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    In this special edition celebrating 300 episodes of The Drive, Peter discusses a variety of popular topics and health interventions and classifies them based on their level of evidence and relevance using the following categories: proven, promising, fuzzy, noise, and nonsense. Peter first delves into the topic of geroprotective molecules, covering rapamycin, metformin, NAD and its precursors, and resveratrol. Next, he explores the significance of metrics like VO2 max and muscle mass, as well as emerging concepts like blood flow restriction and stem cells. The conversation extends to nutrition, addressing questions surrounding long-term fasting, sugar consumption, sugar substitutes, and the contentious role of red meat in cancer. Peter not only provides his current stance on each topic—most of which have been covered in great detail in the previous 300 episodes—but also reflects on how his opinion may have evolved over the years.

    We discuss:

    • Defining the categories of “proven, promising, fuzzy, noise, and nonsense” [3:15];
    • Rapamycin [9:30];
    • Metformin [17:00];
    • NAD and its precursors [24:30];
    • Resveratrol [32:45];
    • The importance of VO2 max, muscle mass, and muscular strength for lifespan [38:15];
    • Blood flow restriction (BFR) training [44:00];
    • Using stem cells to treat osteoarthritis or injury [51:30];
    • Fasting as a tool for longevity (and why Peter stopped his fasting protocol) [55:45];
    • The energy balance theory [1:06:30];
    • The idea that sugar is poison [1:12:00];
    • The idea that sugar substitutes are dangerous [1:22:15];
    • The debate on red meat and cancer [1:28:45]; and
    • More.

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    Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death

    Special episode with Dax Shepard: F1 and the 30th anniversary of Ayrton Senna’s death

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    This is a special episode of The Drive with Peter’s friend and fellow car enthusiast Dax Shepard. In this podcast, which commemorates the 30th anniversary of the death of Brazilian Formula One legend Ayrton Senna, Dax sits down with Peter to better understand what made Senna so special and why Peter remains an enormous fan. This conversation focuses on Senna’s life, the circumstances of his death, and his lasting impact and legacy on the sport of F1.

    We discuss:

    • Peter’s interest in motorsports began as a child [2:30];
    • The drama and dangers of F1 [6:00];
    • What made Senna special [13:00];
    • What Senna meant to Brazilians [24:00];
    • The cause of the fatal crash [28:15];
    • Why Peter is obsessed with Senna [40:30];
    • Being the best versus having the best record [43:30];
    • Senna’s unique driving style and incredible intuition about automotive engineering [46:30];
    • Back to the day of the dreadful race [53:00];
    • What Peter believes caused the crash [1:02:45];
    • Views on dying young, in the prime of life [1:13:00];
    • Senna lives on in his foundation and in safety changes adopted by F1 [1:21:00];
    • Statistics aren’t enough for fandom, and why people like who they do [1:24:15];
    • The biggest difference between F1 today and F1 in the 80s [1:28:30];
    • Senna’s driving superpower [1:30:30];
    • The fastest drivers currently in F1 [1:38:30];
    • Current F1 obsessions [1:45:00];
    • How hard it is to do what the top F1 drivers do [1:50:15];
    • Dax’s love of motorcycles and his AMG E63 station wagon [1:52:15];
    • Awesome Senna mementos from Etsy [2:01:15];
    • What makes specialists interesting, and Max’s devotion to F1 [2:10:15];
    • What Senna might have done if he had not died that day [2:14:00];
    • Michael Schumacher and Max Verstappen are also top F1 drivers [2:17:30];
    • Interlagos in Sao Paulo Brazil is always an incredible experience [2:18:45]; and
    • More.

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    #299 ‒ Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.

    #299 ‒ Optimizing muscle protein synthesis: the crucial impact of protein quality and quantity, and the key role of resistance training | Luc van Loon, Ph.D.

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    Luc van Loon is an internationally renowned expert in skeletal muscle metabolism. In this episode, Luc starts with an exploration of the roles of insulin and triglycerides in endurance exercise, highlighting their impact on skeletal muscle metabolism, and he offers profound insights into the significance of protein in this context. He elucidates how different protein types and forms influence muscle protein synthesis rates, exploring the nuances of protein absorption, digestibility, amino acid quality, and their implications for performance and recovery. Delving deeper, he differentiates between animal and plant protein sources, unraveling the distinctive properties of various protein types, from the differences between whey and casein to the emerging trends in collagen protein supplementation. Moreover, Luc dissects the intricate connections among physical activity, lean muscle mass, muscle protein synthesis induced by resistance training, and dietary protein.

    We discuss:

    • Luc’s background and insights about fuel selection during exercise [3:30];
    • Fuel utilization during endurance exercise [9:30];
    • Fat metabolism, intramuscular lipids, and the nutritional dynamics of endurance sports [17:15];
    • The optimal window for replenishing intramuscular fat stores and glycogen post-exercise [25:15];
    • Luc’s interest in protein metabolism and exploration of amino acids' dual role as building blocks and signaling molecules in driving muscle protein synthesis [32:15];
    • How protein metabolism differs between sedentary individuals and those engaged in predominantly strength training or endurance training [38:45];
    • The basics of how proteins are digested and absorbed, and how muscle protein synthesis is measured [50:30];
    • How factors like food texture, cooking methods, and protein composition impact muscle protein synthesis, and the importance of protein distribution throughout the day [59:45];
    • Differences in whey and casein proteins, and the ability of ingested protein to stimulate muscle protein synthesis [1:03:30];
    • Dietary protein distribution and quantity for the maximization of muscle protein synthesis [1:09:00];
    • Muscle loss with age and inactivity and the importance of resistance exercise to maintain type II muscle fibers [1:17:15];
    • Differences between whey and casein proteins, and the importance of both quantity and quality of protein sources [1:28:30];
    • Optimizing muscle protein synthesis: exercise, timing of protein intake, protein quality, and more [1:37:00];
    • How to preserve muscle while trying to lose weight [1:46:00];
    • Anabolic resistance and overcoming it with physical activity [1:55:45];
    • Importance of protein intake and physical activity in hospitalized patients [2:06:30];
    • Reviewing the efficacy of collagen supplements [2:13:30];
    • Plant-based diets: how to ensure a balance of amino acids, and other considerations [2:20:30];
    • Future research: understanding protein metabolism in the brain [2:23:45]; and
    • More.

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    #298 ‒ The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D.

    #298 ‒ The impact of emotional health on longevity, self-audit strategies, improving well-being, and more | Paul Conti, M.D.

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    Paul Conti is an author and practicing psychiatrist who specializes in helping people heal from trauma. In this episode, Paul returns to The Drive to delve into the intricate relationship between emotional health, healthspan, and lifespan. He first challenges common assumptions about the inevitable decline of emotional health with age, providing strategies for conducting a comprehensive audit of internal emotional health. He establishes a framework for the foundation of good emotional health: a balance between the generative drive, the assertive drive, and the pleasure drive. Paul also explores the nuanced dynamics of motivation, happiness, and satisfaction as it relates to material possessions, draws connections between physical and emotional well-being, confronts the impact of negative self-talk, and describes how making peace with our mortality can foster a sense of hope, purpose and well-being. Additionally, Paul offers many practical insights into initiating emotional health improvements and navigating the search for a suitable therapist.

    We discuss:

    • The importance of prioritizing emotional health as we age [2:45];
    • The impact of emotional health on healthspan and how to foster a proactive approach to emotional well-being [7:00];
    • The discrepancy between outward success and inner fulfillment, and the importance of a healthy “generative drive” for genuine well-being [13:00];
    • A deeper dive into generative drive: impact on human behavior, resilience, purpose, and more [23:15];
    • Evaluating one’s inner self: introspection, self-awareness, challenging societal norms, and returning to the basics of physical and emotional well-being [29:00];
    • Self-auditing tools: introspection, curiosity, and exploring underlying reasons for unwanted behaviors [41:45];
    • Breaking free from destructive cycles by understanding the continuum of self-care and addictive behaviors and remaining curious [50:15];
    • Critical self talk: the malleability of one’s inner dialogue and the potential for transformative change with perseverance and self-compassion [1:00:15];
    • Slowing the anger response and gaining insights into the underlying triggers to achieve lasting change and self-understanding [1:13:45];
    • Foster gratitude and humility by achieving balance between the three drives—assertion, pleasure, and generative [1:20:45];
    • The conflict between intellectual understanding and emotional feelings, problematic comparison frameworks, and the importance of living in the present with intentionality [1:24:15];
    • How making peace with our mortality can foster a sense of hope, purpose and well-being [1:34:45];
    • Advice for finding a compatible therapist [1:43:45];
    • The key components of therapeutic progress [1:57:00];
    • The caricatures of four common patient phenotypes, and how to get through to them [2:05:30];
    • How Paul manages his own well-being and the emotional challenges that come with his line of work [2:15:15]; and
    • More.

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    #297 - AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency

    #297 - AMA #58: Iron: its role in health, testing methods, and strategies for preventing and managing iron deficiency

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    In this “Ask Me Anything” (AMA) episode, Peter delves into the crucial yet often overlooked topic of iron and iron deficiency. He explores why iron is indispensable for the body, explains the repercussions of iron deficiency, and sheds light on the prevalence of this issue and who is most susceptible. Peter outlines strategies for increasing iron levels, covering dietary iron, supplementation, and infusion options, while also discussing the suitability of each approach for different individuals. Shifting gears, Peter tackles rapid-fire questions on creatine and sodium, as well as inquiries related to his book.

    If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #58 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.

    We discuss:

    • Overview of today’s topics and the importance of understanding iron levels in the body [1:45];
    • The importance and ubiquity of iron in the body, and the role of the protein called ferritin [4:30];
    • The processes of iron absorption, utilization, and transportation [9:30];
    • Options for testing iron levels and how to interpret the results [13:45];
    • What does it mean to be iron deficient, and how is it different from anemia? [17:15];
    • Symptoms of iron deficiency and/or anemia [22:15];
    • How prevalent is iron deficiency, and who is most susceptible? [24:30];
    • The importance of consuming an adequate amount of iron daily to prevent deficiency [30:30];
    • The best way to improve iron levels for someone who is deficient [34:45];
    • Iron supplementation: various formulations and potential side effects [37:45];
    • Intravenous iron infusion as an alternative to oral supplements -- plus restless legs syndrome and other topics [42:00];
    • Iron supplementation: who should and should not consider it [44:00];
    • Peter’s approach to creatine and his pre- and post-workout supplements [50:15];
    • Navigating sodium intake: effect on blood pressure, who should use precaution, and other considerations [54:45];
    • Peter’s thoughts about the potential of writing another book [57:15]; and
    • More.

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    #296 ‒ Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C.

    #296 ‒ Foot health: preventing and treating common injuries, enhancing strength and mobility, picking footwear, and more | Courtney Conley, D.C.

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    Courtney Conley is an internationally renowned foot and gait specialist. In this episode, Courtney delves into the intricate world of foot anatomy and functionality. She explores the complexities of the foot, discussing its anatomy, common injuries, and the importance of understanding its structure in preventing issues. She covers a range of foot ailments, factors contributing to them, treatment options, and prevention strategies. She delves into the significance of loading, balance, range of motion, and posture, emphasizing the crucial role of strength in preventing both injuries and falls. Additionally, she sheds light on the interconnectedness of the kinetic chain, from the leg muscles down to the foot, and how issues within this chain can cascade downstream, leading to various injuries and pathologies. Additionally, she provides a comprehensive overview of footwear, discussing suitable options for both adults and children to promote foot health and mitigate potential problems.

    In addition to this interview, Courtney also recorded a series of videos to better explain a number of the concepts discussed such as diagnostic tests that are used to determine mobility and strength and the exercises one should perform to improve the outcomes based on the diagnostics. The interview will be available to everyone while the videos from the gym will only be available to paid subscribers (found at the end of the show notes page).

    We discuss:

    • Why Courtney chose to specialize in the foot [3:30];
    • The vital role of foot strength, function, and health in human movement and well-being [6:15];
    • Anatomy of the rear foot and midfoot [10:15];
    • The development of flat feet, the impact of footwear, and the benefits of going barefoot [19:45];
    • Anatomy of the forefoot, common injuries, and why most injuries occur in the forefoot [23:15];
    • Foot musculature and its role in maintaining foot stability and preventing deformities like bunions and hammer toes [30:15];
    • The intrinsic musculature of the foot, plantar fasciitis, footwear, and more [39:00];
    • Plantar fasciitis: diagnosis, causes, and treatment [51:30];
    • Posterior leg muscles: strength assessment methods, role in ACL injuries, and more [59:15];
    • Lateral and medial muscles: ankle stability, arch support, big toe stabilization, and exercises to strengthen and prevent injuries [1:04:15];
    • Importance of strength of lower leg muscles for gait and preventing shin splints, stress injuries, and more [1:08:15];
    • Tendinopathies and other common pathologies related to the anterior and lateral compartments of the foot [1:13:00];
    • The importance of midfoot integrity, ankle dorsiflexion, and a discussion of gait alterations [1:19:45];
    • Proximal stability and its implications for posture and movement patterns [1:27:00];
    • The age-related decline in foot sensation and strength [1:32:45];
    • Common toe injuries, treatment, and how to prevent further progression of the injury [1:36:30];
    • Preventing falls and managing arthritis with proactive foot care and exercises [1:46:45];
    • Footwear: advice for picking shoes that promote foot health [1:54:45];
    • Footwear for runners [2:05:30];
    • The importance of prioritizing footwear that promotes natural foot movement and strength while considering individual comfort and foot health needs [2:09:30]; and
    • More.

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    #295 ‒ Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D.

    #295 ‒ Roadway death and injury: why everyone should care and what you can do to reduce risk | Mark Rosekind, Ph.D.

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    Mark Rosekind is an expert on road safety and a policy leader with more than 30 years of experience enacting strategic, practical, and effective data-based solutions that enhance driver and pedestrian safety and health in complex environments. In this episode, Mark delves into the persistent issue of accidental deaths resulting from roadway accidents, a concern for those focused on longevity given its consistent risk throughout life. From exploring statistics on car crashes to identifying the demographics most at risk and the key locations of incidents, he uncovers various risk factors including distractions like smartphone usage, the influence of alcohol and cannabis, the dangers of sleep deprivation, and speeding. Mark also provides practical advice for both drivers and pedestrians to enhance safety, while delving into the potential and challenges of emerging technologies such as autonomous vehicles. Additionally, Mark provides valuable resources for listeners, particularly parents navigating the road safety landscape with teenage drivers.

    We discuss:

    • Mark’s background and education, and the profound impact of transportation accidents on human lives [4:15];
    • From sleep science to safety leadership: Mark’s journey in transportation innovation [14:15];
    • Stats on transportation accidents and fatalities [18:00];
    • Historical trends in road fatalities and the key contributors—impairment, distraction, and more [28:00];
    • The demographics of drivers involved in crashes, and the life-saving potential of better driver education programs [34:30];
    • The most critical areas where drivers need to be hyper-aware to protect themselves [41:00];
    • The role of the National Transportation Safety Board (NTSB) in accident investigations, and the importance of data sources like event data recorders (EDRs) in accident reconstruction and investigations [47:00];
    • The dangers of phone use while driving [53:45];
    • How drunk driving was addressed through advocacy and legal changes [1:01:30];
    • The need to address distracted driving and the psychological impact of distracted driving accidents on both victims and perpetrators[1:07:15];
    • Navigating the roads and lowering your risk of accidents: weather, human error, and defensive driving [1:15:45];
    • The impact of impaired driving: alcohol, cannabis, prescription drugs, and more [1:26:15];
    • Mitigating the effects of vehicle speed [1:38:15];
    • The promise and challenges of autonomous vehicles for road safety [1:44:15];
    • Automatic emergency braking (AEB): the effectiveness and challenges of implementing AEB as a standard feature in new vehicles [1:53:00];
    • Sleep deprivation: the impact of poor sleep, drowsiness, and disrupted circadian rhythm on driving [1:58:15];
    • Protecting pedestrians: strategies for reducing the risk of fatal accidents with pedestrians on foot or bicycle [2:02:30];
    • Empowering safe driving: essential resources and tips for parents and teenage drivers [2:14:00];
    • Promoting a culture of proactive safety: parting thoughts from Mark [2:19:15]; and
    • More.

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    #294 ‒ Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu

    #294 ‒ Peak athletic performance: How to measure it and how to train for it from the coach of the most elite athletes on earth | Olav Aleksander Bu

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    Olav Aleksander Bu is an internationally renowned sports scientist acclaimed for his coaching prowess with elite athletes spanning a diverse range of sports disciplines. In this episode, Olav delves deep into the intricacies of VO2 max and its profound impact on performance. They explore the relationship between VO2 max and ATP production, energy efficiency, and power, as well as the impact of low-intensity training on VO2 max. The conversation extends to Olav’s experiences pushing the boundaries with high-performance athletes and the data driven interventions he uses to improve performance. They also dissect the role of lactate threshold, discuss other important metrics to track, and explore the exciting possibility of utilizing a portable VO2 testing device as a practical alternative to traditional lab-based assessments.

    We discuss:

    • Olav’s background, expertise in exercise physiology, coaching experience, and interest in the extremes of human capability [4:15];
    • The processes of energy conversion within the human body and its implications for performance [9:30];
    • Improving movement efficiency, and the importance of mindfulness in training to optimize performance [20:00];
    • The relationship between VO2 max, power output, and endurance performance in different sporting contexts [34:45];
    • How VO2 max is measured in the lab, and why it’s a crucial predictor of both lifespan and quality of life [44:45];
    • Absolute vs relative VO2 max, the significance of functional threshold power in cycling, and the importance of longer duration tests for accurate assessments [54:00];
    • Portable VO2 testing devices as a practical alternative to lab-based tests [1:05:15];
    • The complexities of measuring ventilation and its impact on performance metrics like VO2 max and heart rate [1:15:45];
    • Training interventions to increase VO2 max, and factors that impact performance outcomes [1:23:30];
    • The respiratory exchange ratio (RER) and endurance sports, and how factors such as diet composition and exercise intensity influence RER values and performance [1:32:45];
    • Science-guided training for versatile athletes: maximizing VO2 max, power, torque, and cadence in cycling, and the importance of incorporating diverse stimuli to enhance performance [1:41:00];
    • Physiological limitations on VO2 max [2:02:15];
    • The different energy systems used during work, and other things to monitor like VCO2 and heart rate [2:06:00];
    • Lactate threshold and other metrics to guide your training [2:10:30];
    • Analysis of a lactate power curve: exploring lactate dynamics in endurance training and performance [2:23:15]; and
    • More.

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    #293 - AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity

    #293 - AMA #57: High-intensity interval training: benefits, risks, protocols, and impact on longevity

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    In this “Ask Me Anything” (AMA) episode, Peter delves into the topic of high-intensity interval training (HIIT), starting with addressing some common misunderstandings around this type of exercise and breaking down what HIIT truly entails. He examines the correlation between HIIT and VO2 max, a vital metric for overall health and longevity, and describes the beneficial impact of HIIT on longevity when incorporated properly. Additionally, he emphasizes the importance of building a wide base of cardiovascular fitness, reveals the optimal protocols for incorporating HIIT into a balanced routine, and discusses the risk of injury and other potential drawbacks of HIIT.

    If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #57 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.

    We discuss:

    • Common questions about high-intensity interval training (HIIT) [1:30];
    • The origins of HIIT [3:15];
    • Defining HIIT training and differentiating it from sprint interval training (SIT) [5:45];
    • Why HIIT is often touted as a more efficient way to exercise [14:00];
    • Navigating the nuances of HIIT research: understanding limitations and the importance of a blended exercise routine [20:30];
    • The four pillars of exercise [24:15];
    • Using HIIT to improve VO2 max [26:00];
    • HIIT training for the untrained individual: impact on VO2 max and the interplay between exercise-induced adaptations and potential weight loss [33:00];
    • Sprint interval training (SIT) vs. HIIT: comparing the relative improvements in VO2 max and the impact of longer duration intervals [40:00];
    • Benefits and limitations of HIIT, drawbacks of overtraining with HIIT, and the importance of a diversified routine to increase total cardiorespiratory capacity [44:15];
    • HIIT protocols Peter recommends [58:45];
    • The risk of injury and other potential drawbacks of HIIT [1:02:15];
    • The importance of incorporating a balance of continuous moderate-intensity cardio and HIIT when aiming for longevity [1:04:00]; and
    • More.

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