TMHS 857: Reverse Aging, Prevent Disease, & Live Longer – with Dr. William Li
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January 01, 2025
TLDR: This episode discusses the role of gut bacteria in longevity, specifically focusing on Akkermansia, P9 probiotic strain and four beneficial bacteria. It emphasizes exercise's importance for longevity, healthy diet, reframing chronic diseases, reducing exposure to microplastics, and Dr. Li's elderly uncle's lessons about healthy aging.
In the latest episode of The Model Health Show, host Sean Stevenson welcomes back renowned physician and researcher, Dr. William Li, to delve into the science of longevity, healthy aging, and disease prevention. With a wealth of insights from Dr. Li's groundbreaking studies, this episode promises valuable takeaways for anyone interested in living a healthier and longer life.
Key Insights from Dr. William Li
The Current State of Longevity
- Mind-Blowing Statistics: Over 722,000 individuals aged 100 or older are currently alive, showcasing that longevity is achievable.
- Super-Ager Phenomena: Dr. Li discusses the definition of a super-ager, someone who thrives past age 100, maintaining both health and cognitive function.
Health Factors Influencing Longevity
Dr. Li identifies three main culprits that hinder our quest for a long, healthy life:
Metabolic Syndrome
- Affects about 70% of Americans and includes conditions like obesity and insulin resistance, which lead to further chronic diseases.
- Caused largely by a diet high in ultra-processed foods and added sugars.
Cancer Risks
- With 1 in 2 men and 1 in 3 women likely to develop cancer, prevention is crucial. Dietary choices play a significant role in reducing risk.
- Immunotherapy represents a promising area of research in targeting cancer more effectively.
Cardiovascular Disease
- A primary cause of poor health and longevity, often linked to artery and blood vessel health.
- Blocked arteries can lead to heart attacks or strokes, emphasizing the importance of maintaining a healthy cardiovascular system.
The Role of Gut Health
- Gut Microbiome Connection: Dr. Li emphasizes the importance of a balanced gut microbiome, highlighting four key bacteria found in centenarians that promote health. Notable among these is Akkermansia, which supports gut health and immunity.
- Dietary Diversity: Eating a range of whole foods is essential for nurturing gut microbiome diversity, crucial for overall health.
The Brain Microbiome: A New Frontier
- Recent research suggests that our brains harbor their own microbiome, which can influence mental and emotional health, opening doors for future treatments for neurodegenerative diseases.
- Key bacteria like lactobacillus plantarum are now being studied for their positive effects on brain function, which could lead to breakthroughs in treating conditions like Parkinson's disease.
Lifestyle Elements for Longevity
- Exercise: Regular physical activity is vital; it releases myokines (or hope molecules) that not only enhance physical health but also boost mental wellness and optimism.
- Social Interaction: Building strong relationships and community ties is essential for maintaining longevity and mental health.
Dietary Recommendations
- Incorporating green tea into daily routines can yield numerous health benefits, including enhanced metabolic health and reduced cancer risk.
- Avoid Microplastics: A growing concern, studies have revealed that microplastics can accumulate in the body and linked to increased cardiovascular risks. Switching from plastic to glass or stainless steel can mitigate exposure.
Conclusion: From Knowledge to Action
Dr. William Li asserts that longevity and health are accessible to everyone, not just an elite few. By understanding the factors that influence health and actively making informed lifestyle choices, individuals can take charge of their longevity journey and live their best lives.
For more insights like these, make sure to tune into The Model Health Show with Sean Stevenson and stay informed about practical steps you can take today for a healthy tomorrow.
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You are now listening to The Model Health Show with Sean Stevenson. For more, visit themodelhealthshow.com. The conversation about longevity is about to expand in a big way.
I think you're going to be shocked to find out just how many people are alive on planet earth right now that are over 100 years old. The number shocked me. Our special guest is a pioneering researcher in multiple fields in the field of cancer research in the field of food as medicine and also in the field of longevity.
He's going to share with us what a super-ager is and the real definition of this growing term and a really remarkable phenomenon taking place that you might want to be a part of. He's also going to share the three things that are robbing us, robbing our communities of our inherent longevity. We have a genetic template. We have the ability
to live a long, healthy lifespan much longer than the average age of life today. Our lifespan was extending for decades, upon decades, upon decades.
somewhere around the 1990s that extended lifespan began to reverse. And now the current generation that's being born right now that's already here, we're talking about kids and adolescents, is the first generation that's predicted to not outlive their predecessors. Something is going on. But again, simultaneously,
there are people who are living longer and healthier lives than ever. And we need to get this information into our hands, this education, into our hands and hearts so that we can change this society wide for the better. Now during this conversation, one of the things that my special guest, Harvard trained researcher and expert in particular in cancer research and reversal and also metabolic health,
he brought up the power of green tea. And just to speak to the metabolic benefits, a study that was published in the American Journal of Clinical Nutrition found that participants who had a green tea concentrate before exercising burned 17% more fat than those who didn't. The researchers noted a greater improvement in insulin sensitivity for these participants as well.
But what makes green tea so special is that it improves both metabolic health and immune system health, even dramatically reducing the risk of various cancers. A study published in the journal Breast Cancer Research and Treatment found that women who drank the most green tea had an approximately 20% to 30% lower risk of developing breast cancer.
Now, just to be clear, this is an observational study, but the results are truly promising, while a meta-analysis of 29 studies, published in the peer-reviewed journal OncoTarget, found that people who drink green tea daily were around 42% less likely to develop colorectal cancer. So I know why a cancer researcher, like our special guest today, would bring up
green tea because the data is so rich on its benefits. But there's a certain form of green tea that he also mentioned, by the way, that stands out above the others. And that is matcha green tea. The matcha green tea that I drink is called sun goddess matcha green tea. It's shaded 35% longer for extra alfianine to support cognitive function.
is crafted by a Japanese T-Master, which there are less than 15 of these individuals in the world. And it's the first matcha that's quadruple, toxin-screened for purity. No added anything. No preservatives, no artificial sweeteners. It's just the very best matcha in the world. And it's the sun goddess matcha green tea from Peak Life. Go to peaklife.com or slash model.
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free shipping, free tea samples, and so much more. Plus, they have a 90-day money-back guarantee. If you don't absolutely love peak teas, you get a full refund, and that means you've got nothing to lose and only better health to gain. Again, go to peaklife.com4 slash model. That's P-I-Q-U-E-L-I-F-E.com 4 slash model.
And now, let's get to the Apple Podcast review of the week.
Another five-star review titled, The Fantastic Podcast by Aunt Jenny Five. I just found this podcast in the last six or so months. I'm sorry I didn't find it much sooner. I love the content and format as well as the study-based information that Sean provides. The content is interesting and relevant. Thank you for your hard work and an amazing podcast. Thank you so much for leaving that review over on Apple Podcast. I truly do appreciate that. If you get to do so, please take a moment.
pop over to Apple podcast and leave a review for the model health show. And if you're listening on another podcast app, all good. It's all love. If you can rate and review the show, it truly, truly does mean a lot. And without further ado, let's get to our special guest and topic of the day. Dr. William Lee is an internationally renowned physician, scientist, and New York Times bestselling author. His groundbreaking research has led to the development of more than 40 new medical treatments that impact care for more than 70 diseases.
including diabetes, blindness, heart disease, and obesity. Dr. Lee has been featured on Good Morning America, CNN, and countless other media outlets, including USA Today, Time Magazine, O Magazine, and more. He's the president and medical director of the AngioGenesis Foundation, and he's leading global initiatives on food as medicine.
Let's dive into conversation with the incredible Dr. William Lee. My good friend, my guys, good to see you, Dr. William Lee. Thank you so much for coming to hang out with us. Hey, thanks for inviting me back. It's always great to see you and have these great conversations. Yeah, let's start off with sharing a mind-blowing fact.
about human longevity on planet Earth today. All right, so my research is getting into longevity because it's one of the most exciting topics out there. We're learning more about how to do healthy aging than we've ever known before. And so one of the things that I'm trying to do is to figure out what is the actual fact of longevity. So how many people do you think are alive today who are 100 years old or older?
My guess would be in the ballpark of maybe 25,000. All right. The answer is 722,000 people are age 100 or older today. Mind-blowing fact. Mind-blowing because, you know, like we don't really think about getting to 100 as a realistic or achievable goal. But the fact that there's almost three quarters of a million people who have already done it
without implantable goo-hoo sensors, without being biohackers, without being, all right, it tells you something, right? So that to me is one of the exciting reasons to dive into this whole space. That is very exciting. And just to know again, without all of the, again, there's great innovations that are happening right now, but a lot of people have figured certain things out. And if you could, I also wanna dig in on a surprising fact
that is related to their longevity, and this might have something to do with their gut health. Okay, so I started to get into looking at gut health with gut microbiome, which are the 39 trillion healthy bacteria that are in our gut that do all kinds of things we know, lower inflammation, they release short chain fatty acids, they talk to our immune system, 70% of which is in the wall of our gut,
They text message our brain, the old gut brain axis, control our lipid metabolism, our insulin sensitivity. I mean, pretty much air traffic control for our health lives inside our gut, right? So we're normally thinking about this. I started out looking at gut health in cancer patients. I'm a cancer researcher. And we now realize that if you have cancer and you're being treated with a very advanced therapy called immunotherapy, which relies on your immune system,
Most natural way of treating cancer you can imagine let your own immune system knock it out If you don't actually have the right gut microbiome profile You're not likely to respond to cancer therapy. That's not like optional. That's life or death, right? So I got into that's how I got into the gut microbiome for the other thing that got me into this is wound healing and
A lot of people, if you cut yourself, you and I are probably going to heal pretty fast, but if you have type 2 diabetes and you cut yourself, it might take a long time to heal, and you might have a wound on your foot that you can't see, and that thing will just not heal until it becomes infected.
And then it can lead to gangrene and amputation and all this kind of stuff. So I spent part of my career helping to develop brand new angiogenic blood vessels stimulating ways to quickly heal wounds. Very successful. But then I had a discovery.
with a colleague of mine at the Massachusetts Institute of Technology that certain gut microbiomes, certain probiotics can speed your wound healing. So I'm just telling you how I got into this field. So with that, with wound healing and diabetes and with cancer and treatment outcomes, I started to really take this toolkit.
and start to ask myself, how do we apply this in longevity? And the natural curiosity is, are people who are super-agers. Do they have anything special about their gut? It's the last thing you think about, right? Like some old dude, you know? Like, how are you gonna actually study their gut? Well, guess what? It's no different than actually studying a young dude.
Okay, a young person's got microbiome. You get a swab, you swab your poop, send the tube away. And now, 15 years ago, it would have been very, very difficult to actually study the gut microbiome. We didn't have the software. We didn't have the sequencing. We didn't have the baseline database to even know what to look for.
fast forward to today, we got it. So it's possible to do research now that we couldn't do, you know, 15 years ago. So amazing research. I want to share with your audience has had a study was done in Italy, Bologna, Italy, they looked at adults across all the entire spectrum of adulthood, 20 to 40,
40 to 70, 70 to 90, 90 to 100. And then they actually looked at people who are 100 to 114 super ragers. Okay, that's like the entire adult lifespan. They looked at their gut microbiome and then they used computational biology to ask within the age categories and especially with the super ragers, 100 and above.
Any gut bacteria pop out as super high, like stand out bacteria that you didn't see in other populations. And it turns out for the people who were 100 years old or older, there are four bacteria that are standouts. Want to hear what they are? Yes, I do. Okay.
One of them I know you've heard of, three of them I hadn't heard of, all right? And this is the exciting part, like being a scientist and a researcher, I mean, you really appreciate this as much as anyone else, you know, like the excitement of discovery in biology is like why we do what we do.
You know, it's cool. So, one of the bacteria is called Oderabacter, O-D-O-R-I-Bacter. The second one is called Ocellabacter, like Oscillation Bacter. Another one is Kristin Elensis, okay? And then the fourth one is Acromancia. These four bacteria are standouts.
more of these bacteria in these superagers than you see in any other group and that stand out at higher levels when they get to this age. What do they do? What do they do? Okay, now we know acromancia, boost your immune system, lowers your inflammation. We know that it helps to regulate blood glucose. We also know that acromancia, we actually think that acromancia might actually
interfere with the development of dementia, somehow regulating brain health, and then the latest piece of discovery about acromancia. It's a bacteria. All right, so bacteria have a shell around them. Physically, they're like like a beetle. A beetle's got a little shell, like the bug. There's a particle.
on the shell of acromancia. I don't know if you heard about this. Have you heard of P9? Okay. P is in Peter. Number nine is a newly discovered particle on the shell surrounding acromancia. And you know what they found out is that if you take a live bacromancia bacteria and blow it up into a million pieces, you'd skill it. Like pulverize it. The P9 will still have a beneficial biological effect.
if it's floating around. So it's like a piece of shrapnel from Acromancia that's still biologically useful. And you know what it does?
it causes your gut to secrete more natural GLP1. Wow. Mind blown, right? So now you know, this is the bacteria that's doing a lot of things. And it's even got its own, you know, vest of little tricks in the shell. Anyway, so that's one of the bacteria.
These other bacteria do things like lower inflammation, fight specific, harmful bacteria like E. coli. So you know, think about it, as you get older, most people who get to that elderly age, they don't die of heart attacks, they die of infection.
pneumonia and all this other kind of stuff. So, you know, one of these bacteria seems to really, really mount a good defense against the kind of infection that might take you out. Other ones that you smooth out your metabolism, lower your bad LDL cholesterol and improve your good HDL and lower your triglyceride level. Other ones seem to improve better circulation. These are not surprises. Once you actually break down what these bacteria, these four bacteria,
are involved with in terms of your physical health. It makes total sense. And these guys, these centenarians, and older, okay, because I had never considered when I first started to take a look at longevity, I thought, you know, like 100 is like, all right, that's like a good peak to begin looking at. But I had no idea, like, okay, let's just do a dive on the deep end of the pool and look at their gut microbiome and look at all this stuff. And guess what? You can eat foods that can stimulate these bacteria to grow.
Amazing, amazing. I never even thought about how many people are on planet earth right now that have lived to be over 100 years old. I've never even thought about that question. We know that there are these hot spots that have a lot of civilians, right? And I think it's so fascinating that this research was done in Bologna because this is
The hub of baloney comes from this great part of the planet and the diversity in diet is one of the things that's finally being talked about in regards to blue zones. There isn't a particular diet template that is very varied.
But one of the consistencies, of course, is that these people are eating real food, regardless of the spectrum from different kinds of real food. Yes. The diversity is huge. And also, you know, again, on that range from plant to animal food, that percentage is going to change. But what doesn't change is real food and diverse in all of the real foods that they're eating.
Well, and this is something that makes a lot of sense to how our bodies are designed. If you look at our jaws, you look at our teeth, you look at sort of our digestive system, we are through evolution designed to be omnivores. We can tackle pretty much anything you want to put in. Now, obviously you put bad stuff in and your body's going to respond in a bad way, but good stuff in. So there's a wide range. We've got a repertoire, like we got the mixed martial arts of digestion and processing foods that we're hardwired with.
And that's a good thing, you know? And yes, there are lots of different philosophies and approaches and practices of how to eat healthy, but I think you nailed it. Diversity is key. Yeah. And I'm bringing that specific point up. It's a great segue in this conversation about
the importance of healthy gut microbiome. If you want to improve your gut health, you want to improve the inputs, bring in more diversity of inputs for your microbiome. Because basically, these microbes cannot thrive without their own unique kind of food that they enjoy, and they can't make the good stuff for us if we're not taking care of them.
Right there, you know, like our gut bacteria are no different than any other pet we might actually have in our home. You got a pet dog, pet cat, pet parakeet, pet goldfish, same deal. You got to be feeding them every day. You got to feed them higher quality food if you want them to last longer, you know. And how do our, like especially the furry pets, pay us back with attention, with affection, like it forms that bond, that connection. Well, you know, that's happening at a microscopic level in our gut. Like we,
We now realize that we've got to take care of you know like the pregnant mom saying like I'm meeting for two We're actually eating for 39 trillion bacteria Wow, that's a bar. That's a bar right there. All right. One of the things that I'm excited to talk to about is
You know, you have a very important and distinctive perspective about longevity that is not being talked about today. So I want to ask you from your professional experience, in your opinion, what is longevity really? What does longevity really mean?
So I'm going to tell you how I'm approaching it. And obviously this is a big topic with a lot of people working on it. I respect all the researchers that are actually doing this stuff. For me, longevity isn't just living long. It's not about a number you're trying to hit. It's not like going online and booking a seat in a movie theater that's reserved for you. Like, you can't do that, right? So we all want to live as long as we can, but to me,
In addition to trying to get as far as we can in the journey of life, it's really about how do we live in a way that is enjoyable. We've got not just quality of life, but really joy of living. And that's really what I'm fascinated by. It's really sort of like how do we get there and how do we align that long
runway, along with having a good time along the way, the good quality of life. To me, those two things are really important. People talk about health span, but health span is just a word that goes back to health, which itself is kind of an objective word. It's a term. But when I tell you quality of life and join life,
you're hearing that and you're already imagining what it would mean for you. And so that to me brings our humanity back into it. So for me, one of the ways I'm looking at longevity is really thinking about our humanity, who we are, what's important to us as individuals, as communities, as people along the way. I think that's really how you get a fuller picture of it. So I totally think all the people working in a lab on
the hallmarks of aging and the biological and the cellular, the senescence, the mitophagy, all that stuff. Amazing. They're the building blocks or the bricks being placed into the brick wall to understand what's going on with aging and how to counter unhealthy aging. I'm actually trying to take a little bit of a larger sort of humanity oriented look at it, which is to look at quality. And you know, things that are particular interests to me are cognition, brain health,
So important. Brain's not a black box anymore. It's still a lot we don't know. But did you know since we're talking about the microbiome? Did you know that the brain has its own microbiome? This was theorized for years. But now we know. Now we know. Listen, I went to medical school. I was told in no uncertain terms that the brain is sterile. Sterile environment. Sterile environment. You do a tap
of the spinal cord and if you're tapping into the fluid around the brain there's no way in heck you're going to find any bacteria in that unless you've got meningitis or some kind of brain infection right well now we now have within the last few years like really nailed it down that there is a bacteria ecosystem in our brain
like in our gut, gut brain. And you know what? The brain bacteria are not quite as diverse as in the gut, but about 20% of the diversity of the gut bacteria is also in the brain. Undiscovered country. Think about that. I mean, what could we be doing? I mean, could we be treating in the future neurodegeneration using a probiotic?
How cool would that be? And in fact, there's some good data already like I was really struck by some of these bacteria. So, you know, you get your gut microbiome checked. You get a huge amount of information. Hard to know what to do with if you're not like regularly and if you're not an expert in the field, okay?
But we do know a few bacteria that are standouts. And I think that knowing some of these standouts like the Acromancia, I mentioned earlier, well, there's a new one, a new kid in town called lactobacillus plantarum. Now, if you go buy a typical probiotic, you know, like anywhere you order, you'll find a lot of times it's got lactobacillus plantarum. But there's a version of it that's called PS128. Have you heard of this?
This thing has been shown to level off the symptoms, like pretty much stop the progression of Parkinson's disease. Bacteria, brain, interaction. I don't have the explanation that how it works, but wow. What a phenomenal find, because it opens up a whole new gateway for us to try to figure out how to solve these previously unsolvable problems.
Yeah, it's so fascinating because when the explosion happened in the conversation about the microbiome and it really just kind of rose in popularity and discussion, there's always going to be certain entities that are trying to capitalize on this. And the truth is we still just didn't know very much. At this point, we're really starting to know some cool stuff. Yeah.
But this piece of the brain biome is, this is a revelation. Like this is one of those moments for us to just like, we need to really take a moment and take this in.
For me, it is kind of obvious because if you think about what we are, we are an ecosystem, literally from head to toe. And to think that this one part of our brain is off limits. But we know we have a skin microbiome. We have a gut microbiome, a lung microbiome, heart microbiome, our brain, of course. But the interaction, the communication of all of this is what it's really about and understanding.
that we've now identified a certain species of probiotic, a certain species of microbes that can essentially reverse or put a halt in neurodegenerative conditions. You start to see this interplay. Now, our problem is we tend to like, okay, I just need to take a bunch of this probiotic, and it's gonna solve all the problems. And we have this system, and I want you to talk about this, of medicine and also even supplementation.
can be well-meaning, but is trying to isolate and find this one, quote, miracle cure or the smoking gun in the situation and negating the whole. Because you can bring a powerful thing into, we'll just say, into an Olympic swimming pool.
put a drop in there, but you've got this entire swimming pool that it's fighting against. Yeah. No, no, it's so true. And that's like my approach to research is you have to sort of start with acknowledging the complexity and dive into the complexity to try to find out what might be some of the turnkey things that can still work in spite of the complexity. Okay.
And that's why I think that the microbiome, it's easy to jump to the conclusion by excited, motivated, inspired, and well-meaning people that, oh my God, we got a solution. Let's go create a probiotic and everybody should buy it. Subscribe to it and go to refill it every month or every three months. You know, we're at the tip of the iceberg and the iceberg is really, really exciting because
Every bit we're uncovering is telling us just how important this actually is. But like every day else in science, you go from excitement to wondering like, how do we really apply this and will it actually work? And I can tell you this is a cancer researcher. We've cured cancer in mice over and over again. It's like a no brainer how to do it. To be honest with you, if you're talk to an experienced cancer researcher,
You're a mouse with cancer, no biggie, all right? Translating that to people has been climbing Mount Everest, okay? You can get to the top. People do get to the peak of Everest, but it's not easy and a lot of failures. I mean, the road to the tip of it to the summit littered with the bodies of failed efforts, right? Okay, same thing with all of this. And you know, that's why I'm super excited by where the science of longevity, gyro science is actually going.
You know, recently I gave a keynote in London at a longevity group and they asked me to give some of the state of the art. And I didn't just jump into the latest frontiers of science. I basically said, you know what, we all want to live a long time. In fact, it's the search, the quest for immortality is one of the oldest quests known to mankind. All right. And in fact, I gave this as an example, the first emperor of China,
sent organized squads of his people to go scour the planet, looking for the impure that contained a vial of liquid that he could take that would give him immortality. And, you know, never found it, obviously, and he knew he was going to die, so the way he ultimately achieved immortality is by building 10,000 terracotta warriors to look after his tomb.
And that's like the famous terracotta warriors in China. And then if you look throughout history, there have been the great paintings and sculptures of immortality, the fountain of youth, all this kind of stuff that's been, the quest has been described, right? I mean, even like the Holy Grail, they refer to it, right? But I'll tell you, the situation changed in modern times, I think, when Google created Calico,
the spinoff company, whose mission was to conquer death. Do you remember that? It was like a cover of Time Magazine, like, can Google conquer death? It seemed like a ridiculous topic, but you know what? Actually, quite a worthwhile enterprise. If you want to take investor money, put it into a
high bar, like a really stretch goal and try to figure it out. Listen, we've now actually got the capital. We got brain power. We've got computational biology. It's a worthy thing to kind of look for. And then you fast forward even more. You've got all these people that are beginning to embrace the study of aging.
In order to be able to understand us first, it's not all just about living to pick a number. I know some people say, I want to live to pick three digits and they call it out. I have more modest goals, which is just to understand what's going on when we age and are there ways that we can actually temper that so we can do it better more eloquently, more nobly, frankly.
Yeah, yeah. Thank you for that reframe earlier as well with joy as far as our lifespan and our health span. But being able to, yes, live a long life, but to be able to enjoy the process, the quality of life being the key. And for all of us, we have something that comes up when we think about a joyful life. When you said that, I thought about play.
That was something that I thought about. And so yes, being 80, but being playful, playing with my family, playing sports, competing in my 90s, so on. Do we want to have a long life if we're not able to have the quality of life and to have the joy that we want from this life?
And that's a mindset, right? And you got to be able to look forward to something. By the way, you know that exercise is one of the non-controversial aspects of healthy aging, right?
you gotta work out, you gotta exercise, you gotta stay in motion, you know, the body that stays in, you know, that is in motion, stays in motion, you know, like a basic physical law, true for aging, you wanna get to whatever number you wanna, where you're able to get to, you gotta stay in motion, right, so that's the opposite of the couch potato, the sedentary person, but,
Do you know we're discovering additional benefits that can affect mental health, mental wellness, the ability to feel hopeful based on exercise? Have you heard of Hope molecules?
Listen, we're the show that broke the news. We broke the news with Kelly McGonagall years ago. And I saw, it's gone bonkers on the internet. Hundreds of millions of views with this terminology being popularized. But of course, that data came from some researchers that she was consolidating for us. Well, you know, now it's really becoming clear that regular exercise, the contracting of skeletal muscle,
releases natural chemicals as a consequence of contraction, all right, and they're called myokines. The hope of molecules kind of like the popular nickname for them, but it's aptly named myokines, you know, myo meaning muscle.
Kind is like a cytokine. It's a natural chemical that gets released, it gets into the bloodstream as a biological effect. So myokines released by an exercise circulating a blood go to your brain and they actually make you feel hopeful, optimistic. And what I think is so great about that in this conversation.
is that it actually gives people a different perspective and a different reason to believe that being physically active and trying for exercise is worthwhile as they age.
You don't think about it. Most people who, you know, maybe not that physically active through most of their life when you get to 60 or older and you're going to tell them to go work out, ah, bah, humbug. I don't do that, you know. That's for younger people. I'm not going to the gym. I'm not going, why would I bother to do it? I got this far. Well, look.
You want to be hopeful, man. You want to be able to have a good mood. And by the way, it all interplays with it, right? When you feel hopeful, optimistic, when you're capable of feeling joy, then you're going to want to seek out other people that are like-minded. And now you're socializing. And we know from Dan Butner at the Blue Zones and many other research studies that social interaction is so important for healthy longevity, healthy age.
You want to be with your tribe, man. You want to be with people that you enjoy hanging out with that you get something out of. And you wouldn't want to hang out with people when you feel bummed out or depressed. You want to feel hopeful. I can't wait to see this person.
Also, this is what's possible. It's a different narrative than the one we're indoctrinated with. I'm just being honest with everybody. Every time I see you, you get fitter and fitter. This is true story. One of the big revelations with these mild kinds, these hope molecules,
is the fact that it sensitizes our brain and our biology to more pleasure. So it's kind of like a primary virtuous circle instead of a vicious circle. And so in one of the arguments, first of all,
so many, the vast majority of us know this to be true, that being active makes us feel better. But one of the arguments that come up, because again, we broke the story, bonkers on the internet, I'm grateful for that. And you know, some people are like, well, you know, my best friend works out every day and he's, you know, chronically depressed, you know, and it's the what aboutism. And so there's a couple of things that I want to share in rebuttal, which is why is he still doing it?
You know, just ask that question. What if he didn't have that exercise? How much worse might it be? And also it's not saying it's a, it's the cure for all things that Alas or all of our mental health struggles. But we know as a fact being human, it's one of these epigenetic inputs like our genes expect us to move like life is movement.
And when we're not doing this thing, we're going to have all manner of dysfunction start to show up really forms of adaptation. And so just to keep that in context, because instead of being in the what aboutism, let's focus on, I get to do this thing and to literally produce chemistry that gives me more hope. I get to do this thing and it sensitizes my body and my brain to more of the things that make me feel good or
I can do the opposite. Or I can say, you said it, bahumbug. We're very timely. I'm not for that. I don't believe it. I don't want it, whatever, and choose another path. But that's the cool thing today is that we have the knowledge and we get to choose. And every little bit counts. And that's the key thing. I'm involved with some pretty deep and very heady types of research.
But I don't want to talk to people. I try to bring it to human levels, things that people can understand, things that are affordable, things that you can actually achieve, you can reach for. Because you know what? There's a lot of stuff that's really cool in research, but in particular, things that are discovered that are, you know, we don't know how to actually attain that or might be super expensive. I don't think quality of life and longevity are reserved for a subpopulation of people who are privileged to have a lot of money.
That's not it at all. In fact, most of these 722,000 people who are 100 and older are not part of the elite clubs, you know? They're ordinary people. And I think that tells us something. You don't need fancy to get to where you want to be in your life's health and longevity goals, but you need to be sensible and you got to need to be practical. You know, like, I don't know if I told you this, but my great uncle lived to 104.
Completely healthy mentally intact in China and I went to his 100th birthday party All right, which he planned by himself. He made the guest list. He chose a restaurant. He planned the meal and he hosted it. Okay, amazing and I Asked him before his birthday. I went a little bit early to go visit him and
You know, we were having a conversation and I said, you got to tell me what's the secret to longevity, right? I mean, how do you get to be a hundred? He was almost a hundred, like days away. And he said, you know, I don't really have an answer for you, which is honest and I think most people say the same thing. But he did tell me three things that he felt contributed. Number one, he said, I don't let things bother me. I let him roll off my back.
I always remember him telling me that and he's like, I don't get pissed. I don't hold the anger in. I don't stack. You know, it's not that important. He's like, I might not be happy about it, but I let it go. Let it go. And so he's already talking about a mindset.
where he's not going to get too upset about things. He's going to have enough mental awareness and mindfulness. They think not everything matters and he's going to try to lower stress. That was one thing. Second thing I remember he told me, he lived at the base of a T mountain and he knew every picker and the season and he knew all the people that
And he's like, I drank tea my whole life, you know, and he was drinking at least five or six or more cups of tea a day. He was just sipping it all day long. He's like, green tea is my life. And of course, now we know there's many benefits, clinical studies out of what you've shown. The persistent benefits of drinking green tea with the catechins and the polyphenols and for matcha, even the dietary fiber in it.
So he attributed to that and then he said, you know, to drink my tea every morning, I get up and I he would walk up this trail, the stone trail, uneven trail up to the this tea temple, like this like this overhang. It's like basically like a picnic area that he would walk up to to get his tea for the day.
All right, and sit with his buddies. His other really well-aged buddies to sit there and socialize, right? So he's exercising. He's drinking tea, staying in motion, having the right diet, and having the right mindset. So, you know, I always remember this. You know, ultimately he passed. He had a stroke, but I mean, he was really fit all the way to the end. He had a very supportive social network.
I lived a lot of his family and friends, but he had people that took care of him and he took care of them too. And so these are the recurrent themes. And yeah, I think mitophagy is important. I think that NAD is important and sirtuins are important and all that kind of stuff. Those are the little mechanisms that are going to add up. The hole is going to be much greater than some of those parts, but I'm looking at
You know, my research right now, I'm actually looking at like, what is quality? What is it like in people who have actually gotten there? What can we discover using the modern tools to figure out some of those aspects of longevity and quality? And if you can line both of those things up, like that's exactly the shot I want to take. Yeah, I went on an adventure with you and also with him and that making that climb to get to each day.
He built in movement into his nourishment, right? In the community piece and the mindset piece, I don't think it could be overstated how important it is to have a youthful mindset or you use this term earlier. And I want to ask you about this again. You said super ager, right? And I think a lot of people might not have heard that term before. So what is a super ager?
Well, I think this is the term that has been coined by longevity experts who study aging in the population level. And kind of like what we were talking about, the centenarians, people get to 100. At one point, certainly when I was younger, I went to medical school, like, oh, can you get to 100?
Most people can. I mean, maybe you've got one or two people that are really old. Obviously, I had no idea like so many people were getting to 100. But I think once you breach that 100 mark, once you cross that line, all right, now you start entering super-ager territory. And super-agers or super centenarians are people to get to 110, 11, 12, 13, 14. I mean, those are the people who are getting to the summit.
Okay, and I don't think there's a strict definition. I do think it's in that 10% of the 10% You know the tippy top of all the people who age and I think that the superager probably also includes people that are actually very Vibrant along the way you're not counting I don't think you'd call a superager somebody who's in a coma for the last 10 years of their life
That's not super. Got a quick break coming up. We'll be right back. In the conversation about longevity, we want to remain youthful from the outside and the inside. We don't want to have a youthful appearance, but a very, very old heart or a very, very old brain.
We want to make sure that we're taking care of ourselves from the inside out. And there are certain foods that are well-established, not only in peer-reviewed data today, but have been utilized for thousands of years for their longevity benefits. More recently, a study published in Advances in Biomedical Research found that Royal Jelly has the potential to improve spatial learning, attention, and our memory. In addition to being antimicrobial, anti-tumor, and anti-inflammatory,
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Now, having that incredible insight that experienced to be able to talk with the family member and to interview him upon his 100th birthday, that's priceless data, right? On the other side, we've got a sound body of data on what's robbing people of their longevity as well. So let's talk about if you can, can you share with everybody? What are three things that are robbing people of their longevity today?
Oh, yeah. I mean, look, there's a big movement with a lot of interesting, super exciting pioneers trying to figure out how to extend the number of years they've got. But actually the best way to live long is to dodge, prevent, thwart the conditions that are going to rob you of your life. They're going to cut you down short. And if you can dodge those, what are those things?
cardiovascular disease, metabolic syndrome, diabetes, cancer, just to say a few things. If you got any one of those three things, you're probably not going to make it as long as you would like to. Chances are because you've got all these other conditions which are we think largely preventable with diet and lifestyle. Genetics for cancer plays maybe 5% of the equation. Sure, screen for cancer genes. That would be good information for you to know. But honestly,
If you didn't have the tools for screening, just live a healthy lifestyle. Avoid things that are carcinogenic or toxic. Eat healthy or hold plant-based foods primarily. Eat diversity. Watch your gut microbiome. You'll make it a lot of the ways and dodge the cancers that you can. And if you do have one of these diseases.
You know, this is an interesting conversation I had, you know, I was at a strategic retreat from my nonprofit, and we were brainstorming, like literally just got some really smart people in the room to have a roll sleeves up, have a conversation about like, what are we thinking about chronic diseases?
And somebody you might know, do you know Rupi, Ojla, the doctor's kitchen? He's in England. He brought up an amazing point because he was one of my guests. He said, you know, in medicine, because he's a doctor like me, we're trained that chronic diseases, you never stop treating chronic diseases. That's why they're called chronic. We don't think of reversing and we don't think of coming off medication. We think of just lifetime, nonstop, endless prescriptions.
And I thought how profound that topic was, you know, like, okay, you've got diabetes. You ain't reversing that. You're going to be on insulin or whatever other medication forever. All right. You've got cancer. Cancer is a chronic disease. You're going to be treated into your dead heart disease cardiovascular disease. You're going to be in statin forever. And you know, that's just actually the wrong way to think about
Our health, when it comes to longevity, shouldn't we be flipping the script and saying, it's only a chronic disease if you let it become chronic. Why don't we take an illness and reverse it? Can we reverse engineer it back to your healthy state? And then you can get back on the journey to go to your destination. It's like a flat tire.
You're not going to just keep on rolling down the highway with a flat tire until your car breaks down, right? You're going to pull off to the side of the road, fix it, get the tire back into shape, then before you get on the road, the reversal disease is an under-appreciated concept. We do know you can reverse.
type 2 diabetes, in many cases. We do know that you can reverse cardiovascular disease and certainly you can restore the resilience of your cardiovascular system. We are beginning to think that you can actually manipulate brain as well to be able to regenerate the brain. I know that if you talk to most neurologists and
You know, the mainstay of people are saying, it's just like you were saying about like, oh, the depression is not going to work. You talk to people who are neuroscience. They're pretty at the state of the art. They're pretty optimistic. You know, like one of these days, not what are going to be prevent. We should be able to reverse some of these neurodegenerative diseases. And that's the
hope molecule directed way of thinking about our long-term health. We should be able to just, actually, I think we should be reserving the term chronic disease, okay, non-communicable chronic disease like diabetes and cancer and cardiovascular disease. We should be reserving those for the few cases that can't be reversed.
I love that. I love that reframing, reframing, being mindful with the labels as well. And I love that analogy of the flat tire because our system is sort of like you've got this flat tire. Let's put a little air in it. Next day, put a little air in it. Just keep putting a little air in it forever in perpetuity until again, we're not fixing the leak.
we're not fixing the leak or changing the tire, we're just putting a little air, not even completely getting the air pressure correct. Just putting a little bit in there, messing around, you might put too much, too little, but you're just still on even. And it's still not riding right. The tire is still flopping around when you're driving, you know something's wrong. And you learn to live with that. And I just think that in the gestalt of the conversation that's going on in our nation, and I think around the world, it's time for us to reframe how we think about healthcare.
just go along the costs of treating chronic disease as chronic disease of forever diseases. No country can afford that. We can't afford that. And at a human level, on the individual, family, community level, we can't afford that either. Yeah. All right. This is a good segue. Now let's get very specific. Give me three specific things that are robbing us of our longevity. Let's just bullet point them. What's one thing that's taken away? Metabolic syndrome.
Okay, Metabox syndrome is sneaks up on us. It's one of those things that, you know, you might think you're okay. And then one day you realize, you know, I'm not, I'm not so okay. What we don't realize is that what's been going on because of lifestyle and dietary choices and lack of exercise and all kinds of other lifestyle mediate things. You've built up a body of excess harmful visceral fat, even if you're skinny.
It's the fat inside the tube of your body. Even skinny people can have a lot of excess. We used to call it skinny fat. And that fat is inflammatory. That inflammation actually sets off a chain reaction in your body. And you might not even know it until you start
having insulin insensitivity and you start having gaining weight and you start having poor circulation. And by the time most people are diagnosed with metabolic syndrome by their doctor, big waste size, high blood pressure, high fasting blood glucose, high cholesterol, that's the definition of metabolic syndrome, you know, you're already way down the line.
And again, that falls right into the trap of the chronic disease. Oh, you're headed towards type 2 diabetes. Not much you can actually do unless you really take some radical changes to your lifestyle. But listen, that's the moment where you can actually
get off that highway to disaster, take the exit ramp and head back to where you started before you got into danger zone. All right. Don't just keep barreling forward, but that's one of the things metabolic syndrome that leads to, you know, it's sort of the ripple effect of lead getting once you get to a metabolic syndrome, all the dominoes to get locked down, all the ripple effect, the tsunami that occurs is all disease. And one disease makes the other diseases.
more and more disastrous, okay, which then creates suffering and then ultimately will cut short your life, all right? So that's one really, really clear cut thing. And, you know, metabolic syndrome probably affects about 70% of our country. You know, that's a huge amount. Being that metabolic syndrome is the number one thing, and it was no particular order, but that's robbing our longevity.
What is the big culprit or the big contributor with metabolic syndrome? What is that thing that's in our culture that's led to skyrocketing rates of metabolic syndrome? What is it? I think it's really the unconscious habit of eating ultra-processed foods that have a lot of added sugar and other additives that wreck our system.
And by the way, these are the things that we all grew up with. We live in modern society and since the 1950s, 60s, 70s, 80s, 90s, you know, the big revolution, the industrial revolution hit the food system to make foods cheaper.
more widely available, more shelf stable, you know, it's beneficial. Well intention. Okay. And tastes really great. And so, you know, engineers went there to figure out, well, what chemicals can we add, you know, to make it really tasty. So, I mean, look, even for those of us who are very, very health conscious and can speak authoritatively about like the evidence of what a good healthy diet should be more like.
The reality is, is that when you're a kid and I was a kid, we loved product X, Y, and Z that we saw on television. That we got in Halloween, our Halloween pumpkins went trick-or-treating. That we looked forward to when our moms took us to the store at the checkout counter, we wanted to grab something. Can I have one? Look, we're all the same. This is not about
big food conspiracy. This is really about that was a time when this explosion that was considered innovation came about. Long shelf life, cheap, widely available, tasted really great. I mean, it was pretty cool at the time. Now it's not so cool. And I think this is really where the social barometer is beginning to
reset itself to say, you know, we need to be having a conversation about this now. And to ask, are we doing more damage to ourselves by not acting to be more progressive to align what we know about health with our food system? And that's one of the reasons I'm really glad about some of the conversations that are going on. Yeah. Yeah. Me too. Thank you for sharing that. Immediately conjured up ideas, you know, when I was a kid of
Loving these instant pizzas, you know, the frozen pizzas. Totino's. Oh yeah. Love to know about that. The Totino's pizza roll, but the Totino's pizza is a really bad pizza experience, but you develop a taste and a knack for it. I ate so many tombstone pizzas, which is a terrible brand name.
By the way, Toon Stone, Red Baron, but we always had frozen pizzas. And again, being a kid, that's awesome. But today we know that that's not so awesome. But speaking about that, the fact is that
Maybe this is why people in our generation need to be stepping up even harder, not only on our own behalf, but on behalf of children. Because if you think about it, we didn't know better at the time, but now we know better. And so why should we be subjecting the young people of today to maybe a fate we can't, we got to deal with the backpack that we were handed a long time ago.
All right, and I think it's reversible. We're all hardwired for health. We're all hardwired for healing. It's never too late to change to try to get back to basics. But I think for kids, we owe it to them to give them a clean start. I love that. We're talking about an issue of informed consent on our part with food as well. Number one, metabolic syndrome. Number two thing that's robbing us of our longevity.
Cancer. Cancer is I'm a cancer researcher. If you look at the statistics, one in two men are going to develop cancer in their lifetime. One in three women are going to develop cancer in their lifetime. So think about it. You go into with those stats, you go into an elevator with a bunch of people, you know, on your way to a holiday party or whatever, where you're going to go. I mean, you look around and you like, my gosh,
This is a terrible statistic, right? But actually, a lot of cancers are preventable. And you can dodge colon cancer and breast cancer and a lot of other cancers. If we only had a better immune system, better control over our circulation, so we're not feeding cancer with our blood, with a new blood supply. If we were able to have diets that killed off cancer stem cells,
If we had more antioxidant opportunities to neutralize those free radicals that would cause oxidative stress to trigger mutations in our DNA, we can fix our DNA as well. If there's ways that we could achieve lower inflammation, which is the gasoline,
to cancer. You know, you might have a tiny incipient cancer. You have inflammation on top of that. Okay, now you're basically pouring gasoline onto the embers of a fire. It's going to roar. And then immunity, our immune system, I read about this in my first bookie to beat disease, we are hardwired for health. We've got five health defense systems. If we could actually keep those shields up and fortify them,
and tend to them like we would with the gate to our house or the locks in our window or a lock on your door. You know, we'd actually get a lot further away. We'd probably dodge a lot of cancers. And there are foods that can do it as well, diet and lifestyle. It's not just the food, but food actually, we now know there are certain foods that can actually have a pretty profound effect. And so this is another example like metabolic syndrome, like this stealer of years.
Okay, this robber baron of longevity is cancer, which seemed to be so nefarious. Did you ever see the latest Denzel Washington movie called Equalizer? Equalizer 3? Yeah. So there's this Italian guy who basically said, oh, this organized crime locally is like cancer. There's no cure.
You know what? It was a great line in the movie, but in fact, there is a cure to cancer, and we know it now. I mean, as a cancer researcher, I'm seeing it in motion. We're not quite there yet, but with immunotherapy, I've got to tell you, if you want to see an amazing story that's based on science, go check out the Instagram account of a person that goes by the handle, The Brainy Blonde.
Okay, she's blonde, very smart. All right, that's like a trip on tundra, but she had brain cancer, glioblastoma, death sentence. Nobody survives more than one or two years with that things. She's going on almost seven years, cancer free.
And you know what she did? She took a peptide vaccine that boosted her own immune system. All right. And that was able to get her through. So in the future, this is what we're going to be able to do to conquer the scourge. That's still treatment much better to prevent it in the first place. So you don't have to go through that pain and suffering.
Yeah. Awesome. All right. We got one and two checked off. What's the third thing robbing us of our longevity? I think cardiovascular disease, you know, and like when people don't understand card, I'm a vascular guy. I study blood vessels. So this is like right in my wheelhouse.
You know, you got 60,000 miles with the blood vessels in our body. These are the highways and byways that bring the oxygen that we breathe and the nutrients that we eat to every single organ, every single cell in our body. So if your blood vessels are healthy, you got a chance to be healthy and rest your body. But if you got sick blood vessels,
ain't no way you're going to be able to optimize your health because your delivery channels for oxygen nutrients aren't actually going to be able to fulfill what your body actually needs for optimal health. And so cardiovascular disease is not just heart disease.
not just stroke, but really a compromise of the circulation anywhere along the way. That's a long journey, 60,000 miles. If you pulled out 60,000 miles worth of blood vessels out of your body and line them up end to end, that would form a thread that would encircle the earth twice. You could orbit the earth twice with that thread of blood vessels. That's in a single human adult body. All right. So this is why
I think cardiovascular disease, which robs us of good circulation, is so diabolical in terms of sthelia. So what are some of the consequences where we know it steals us? Well, if you get blockages in your heart, you're gonna actually have not as strong a pump of your heart, not just a heart attack, but you actually compromise the muscle contraction of your heart. It's like your bicep that can't lift quite as much. All right, it's called ejection fraction. Your heart just can't inject as much blood.
that leads to heart failure. So what you really want to be able to do is to preserve the pump, the muscle function of the heart as much as possible. We can measure that with a sonogram of the heart to call it a cardiac ultrasound. You can measure that. You can see that. We do that every day in the cardiologist's office. And of course you get other problems of circulation in the heart. You can have heart rhythm problems. People always think about cardiovascular disease like heart attack.
Actually, more commonly you have an arrhythmia, meaning the rhythm, the beat of the heart. Listen, whether you like rap or Beethoven, you're listening to a rhythm. The fact that the rhythm has a pattern and you're digging that pattern, that's what's important for music, also equally important for the heart. And when you actually have vascular problems, you can affect the rhythm of the heart. When the heart starts to quiver or fibrillate, that's what we call it,
That can lead to sudden death. Rob you instantly. Boom, you drop. Bye bye. All right, that's why you use a defibrillator in the mall or in an airplane or an airport. Okay, that can be lifesaving because you're putting the rhythm back, but you got to have a good cardiovascular system. You need good blood vessels to be able to flow. And of course, blockages to the heart. You block that blood flow. You know, that's like putting a road block up and a busy traffic lane, a highway that's flowing. Suddenly you got rush hour. Now traffic slows to a halt.
All right, and now you got a parking lot. And when you got a parking lot on blood flow in your heart, game over. You start killing heart cells, muscle, downstream, and then, you know, like you're really compromising your quality of life, and that ultimately will lead to other problems as well. Same thing I told you about the heart can happen in the brain. So cardiovascular, if you think about your heart, you think about your brain, listen, these are the three things that we talked about, metabolic syndrome, cancer, and cardiovascular disease that
are so obvious that they rob us prematurely, okay, of the life, the longer life that we should be having and because they are all so tied to diet and lifestyle. And that's the one thing that in medicine, your medical doctor,
who went to training in medical school, we are not taught. I'm telling you, you know, as a card-carrying doctor, I received like a week's worth of nutrition, all right, when I was in medical school. And nothing in lifestyle. You know, hopefully that will change, but this is why, you know, podcasts like this, programs like this, YouTube programming like this, this is what we are trying to do is to educate people that the solution to health lies first in our own hands.
Boom. All right. So we've got these three things that are robbing us of our longevity. And we've got some pretty good data at this point on the causative agents. And again, it's not a smoking gun situation, even if we're talking about cancer. But smoking is a gun. Boom. Come on now.
But adding that in, that carcinogen along with carcinogens in our diet, in our environment, lack of movement, the list goes on and on, we start to create an environment where cancer can thrive, right? So with this last piece with cardiovascular health, I want to ask you about this because a fascinating study came out recently in the New England Journal of Medicine and attract the cardiovascular health of over 250 patients.
They found that there were plastics, microplastics detected in the carotid artery plaques of 150 of these patients. The conclusion of the study stated, quote, patients with carotid artery plaque in which micro and nano plastics were detected had a higher risk of composite
Myocardial infarction, stroke, or death from any cause after 34 months of follow-up than those in whom micro and nanoplastics were not detected." What do you have to say about these microplastics?
All right, so look, we are surrounded in a plastic world. It's really impossible to avoid plastic. It's one of the big industrial revolutions to produce plastic. It's everything in our toothpaste or toothbrush to our car seats, to our carpets and our clothing. It's everywhere.
So in our dishwashing soap, it's in your shampoo, all right, it's everywhere. And most people are becoming aware of how much it gets into our body. So we typically, and this is coming from a study that looked at this as well, calculated the typical American in just about a credit card's worth of plastic every week.
every week, all right? And you're like, I don't wanna be in a credit card every week. All right, now you are focusing your attention on what you can do to cut down your exposure to plastics. Now these plastics are everywhere, but they're in some obvious places that we can get into our body. How many people need with a plastic silverware at a picnic or a plastic plate or a cup, a plastic cup, right?
You go to a ball game, you go to a rock concert, you're going to get something to drink. They hand it to you in a plastic cup. Besides tossing that cup out and going into the environment, not being good for the planet, some of these microplastics shed right into our food. We eat or drink it and it gets right into our body. In fact, now we know.
It's not just in the plaque of the artery, the carotid artery. I won't explain that sitting in a second, but I'll tell you, we can detect plastics in the blood. So let's define a microplastic. A microplastic is a particle plastic that is about five millimeters or less. That's about the size of a little bit like smaller than a grain of rice. A nanoplastic is smaller than one micrometer.
1,000 times smaller. All right, you can't see those. All right, but we can detect these. We never used to detect them, but now we know that it's possible to detect them in regular blood. The study you just cited in the New England Journal came from Italy from
Cardiovascular people that were looking at patients who had blockages in their carotid arteries. So you got two carotid arteries left and right. They are the big channels that bring blood from the heart right to the brain. They're absolutely critical.
And they can get narrowed just like any other artery. If you know you've got a lot of cholesterol, a lot of cholesterol plaque, a lot of lipids, I'm just kind of clogging it. It's like the clog sink. Alright, now it's the clog sink that brings blood to your brain.
So, those patients come to attention because they wind up having mini strokes or TIAs or real strokes or they wind up dizzy and you go to the doctor and the doctor does an ultrasound and they look at, they're supposedly looking at a clear carotid artery, a clear tube. Oh my gosh, it's narrowed.
It's narrowed down to 85%. We got to do something about it so you can pick them out. Wow. To find out that in some people you can find microplastics or nanoplastics embedded in the plaque.
That is frightening. Okay. I mean, it's just like you ever go out to this beautiful in nature You're taking out hike in the woods. You see this clear stream Oh, man. Well, how beautiful is mother nature's calming? And then you kind of like walk around the bend and there's like a bunch of plastic cups all piled up on the side go man. That's terrible
That's what's going on in our blood vessels from these microplastics. And that study, that one study was the, you know, I would say that the turning point for me anyway, to realize that this microplastic thing, which we didn't have any evidence, quote, evidence before this, that, you know, it was going to be bad. We thought it was going to be bad. Now we know it's not just an increased risk of fatal heart attack stroke. It's fourfold increase, four X.
Okay, that's what that study actually showed. Alright, now, let me just tell you something else. Not only have we detected microplastics in the bloodstream and in plaques, but other studies that have come out since that one have shown you can detect microplastics in the brain.
brain. Now, not only, and so much microplastic, you can take a kitchen scale. You know, the kind of scale you'd measure like flour out to make a cake. All right. And you can measure the difference between on a chicken and a scale, a brain with microplastics versus a brain that doesn't have it. That that's how much accumulates. We've also found it in the placenta, pregnant women. The placenta is the nutrient connection between mom and baby.
Whoa, you're saying the moms actually have it. That means the fetus probably is affected. The baby is also going to be affected. Are we saying like even before day one, like children are actually getting embedded with microplastics. We haven't looked yet. It's going to come out at some point. Once people start looking, we're probably going to find it. They found microplastics. And for the guys here, like,
I'm not scared of any microplastics, you know, big tough guys. What have I told you? We bring you finding it in the testicles, okay? We're finding it urologists who are doing surgery on the penis are finding microplastics embedded in the penis. How does it even get there? You speculate? We don't really know, but I'll tell you, it's in there, okay? They're finding microplastics in semen.
How does it even get there? All right, so I'm just telling you, like now that we know the totality of all this, here's some practical things you can do. All right, number one, don't use plastic utensils, don't drink out of a plastic cup, don't drink water out of a plastic bottle. I mean, it wasn't so long ago when I went to vacation, it was hot, you know, by the beach or someplace, and I would just get a bottle of water someplace.
You know or and and and why not you got to get to stay hydrated Yeah, but please hydrate yourself without microplastics being shed into the water like that's not what you want to be doing Guzzling it right down all those microplastics. Another thing you can do is don't buy food that is packaged overtly in plastics Now a lot of food does touch plastics like in a factory again another strike against ultra processed foods usually packaged in plastic
It's in a box. You open the box. It's packaged in a bag. It's a plastic bag. You're going to have particles in there and you're going to be eating them. Plastic bottles, you know, like, okay, we already know. You should cut down or cut out soda, added sugar or sugar-free. It's not good for, you know, those non-nutritive sweeteners and not good for your microbiome.
But I mean, come on, how many soft drinks or sodas are being consumed today? I mean, these are entire aisles in the middle of the grocery store with plastic bottled beverages that people are drinking on vacation, at home, at birthday parties, at holiday parties. So cut those out. And then the other thing that's really practical for me is don't buy those storage containers for your leftovers that are made out of plastic.
right? So you went to all this trouble to buy fresh whole ingredients from your farmer's market and you're cooking it in your regular casa stainless steel pans or your cast iron pan doing all the right things and then you got some leftovers you're going to eat the next day and what do you do? You're going to take what's left over this delicious food that you've cooked and healthy as well and you're going to stick it in a plastic container that's got a plastic lid the next day you're going to bring it to work and heat it up in a microwave to just force the plastics into the food come on
So, please throw those away, get pyrex or glass containers. I think the cap, it's really hard to get a glass cap, but if you get a wooden cap or a plastic cap is probably fine for those containers, but do not heat plastic with food in the microwave. These are just some basic things that I think are important. Oh, you know, like high school athletes,
You see them all running around with these plastic water bottles. Let's change them out. Swap them out. Stainless seal, good, glass, also good. I just think that this is one of these things where we didn't know better before. Now we do. So there was an excuse before of what we were doing because we were ignorant.
Now, we have awareness of this problem. Now it's time to do something about it. That's right. That's right. Knowing it's half the battle is coming up for me. Shout out to G.I. Joe. The other half is the doing. And so our awareness is there. You've covered so much ground for us today. You've taken us through a virtual movie here, you know, like truly, like when you were sharing some of these things and talking about
how magical and how interesting biology is for people like ourselves, just like I was on the edge of my chair, like what is he gonna say? This is so exciting. And I just appreciate you so much for leading the charge and asking powerful questions and investigating and sharing what you come up with and inviting so many other people into what you're doing as well.
you've been focusing more on, and I'm grateful for this, your YouTube channel as well, and sharing some really profound information there so people can check you out on YouTube, look up Dr. William Lee, and is there anywhere else for people to connect with you, get more information?
Yeah, well, check me out on social. My handle's at Dr. D. R. William Lee, L.I., from my website. You know, and I do these periodic master classes. And by the way, my YouTube channel, I really started to double down on my YouTube in a particular way because I pay attention to the questions that people send me, the concerns they send me. And what I've been doing is digesting what people are interested in.
Then turning that into the things that I want to put on my YouTube channel like as a way of answering the questions You know, I wish I could answer everybody's questions one-on-one I wish I could sit across from people like you and we can have a long conversation about this But you know one of the beauties of I think the modern technological age of media with YouTube is that you don't have to be a TV star or a news reporter or I mean look we can
If you're responsible and you're conscientious and you want to communicate something important to people, we can do it on YouTube. So I welcome anybody to come on, subscribe, hit like, all the usual things. And the same thing, by the way, your YouTube channel is phenomenal. I think people should really kind of take advantage, by the way, of podcasts, but also realize that the video version is a completely different way of appreciating the same conversation. I echo that.
And this is so awesome again, just to hang out with you and to catch up and I'm excited to see what you do next. I appreciate you. Thanks very much. Dr. William Lee, everybody. Thank you so much for tuning into this episode today. I hope that you got a lot of value out of this. This conversation is so inspiring and so timely. We need to up level our thinking.
and not just think about mere survival, but how can we truly thrive as a species, as an individual, as a part of a community. And I truly believe that this is possible, but we need to get the right education into our hands and hearts. And being able to connect with individuals like Dr. William Lee is truly, truly a gift. This is something that, again, just thinking back before the smartphone paradigm and the podcast paradigm,
getting access to information like this for most people was extremely, I'm not going to say impossible, but extremely, extremely difficult. But now today, thanks to the right use of technology, we can all get this education right there on our phones. And this speaks to what are we doing with the opportunities and the technology that we have at hand, because it can also be used for great detriment.
And so moving forward, I challenge you to truly focus on taking back control of your time, utilizing technology for your betterment and also making it a mandate, moving forward to proactively, intentionally spend more time outside, spend more time face to face with your friends and family and the people that you care about.
It is clear in the data. It is one of the most powerful, if not the most powerful thing that determines how long we're going to live and how long we're going to live healthfully. So invest in those relationships. We got some epic master classes and world class guests coming your way very, very soon. So make sure to stay tuned. Take care, have an amazing day, and I'll talk with you soon.
And for more after the show, make sure to head over to themodelhealthshow.com. That's where you can find all of the show notes. You can find transcriptions, videos for each episode. And if you got a comment, you can leave me a comment there as well. And please make sure to head over to iTunes and leave us a rating to let everybody know that the show is awesome. And I appreciate that so much. And take care. I promise to keep giving you more powerful and powering great content to help you transform your life. Thanks for tuning in.
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